Association Between Chronic Renal Failure and Thyroid Hormone
Background: The idea of the study is to follow the relation between CR.E and thyroid hormones. Material and Methods: The levels of serum urea , creatinine ,total thyroxin (TT4) , Tri-iodothyronine (TT3) , free T4 (fT4) , freeT3 (fT3) and Thyrotropin (TSH) were measured in the serum of 80 Patient...
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| Format: | Article |
| Language: | English |
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College of medicine/ University of Diyala
2019-11-01
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| Series: | Diyala Journal of Medicine |
| Subjects: | |
| Online Access: | https://www.djm.uodiyala.edu.iq/index.php/djm/article/view/430 |
| _version_ | 1797569019520221184 |
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| author | Hameed M Majeed Mazin Razooqi Mohammed Nabeel Khalid Mohamed Ali AL-Wandi Fatimah Kadhim Ibrahim |
| author_facet | Hameed M Majeed Mazin Razooqi Mohammed Nabeel Khalid Mohamed Ali AL-Wandi Fatimah Kadhim Ibrahim |
| author_sort | Hameed M Majeed |
| collection | DOAJ |
| description |
Background: The idea of the study is to follow the relation between CR.E and thyroid hormones.
Material and Methods: The levels of serum urea , creatinine ,total thyroxin (TT4) , Tri-iodothyronine (TT3) , free T4 (fT4) , freeT3 (fT3) and Thyrotropin (TSH) were measured in the serum of 80 Patients with varying grades of chronic renal failure (CRF) ; and 40 healthy individuals . They were divided into 3 groups as : Group 1 containing 40 healthy individuals as control group; Group 2 containing 40 Patients on conservative management ; and Group 3 containing 40 Patients on Regular haemodialysis therapy.
Aim: The aim of the study was to investigate the association between chronic renal failure and thyroid function.
Results: Groups 2 and 3 showed significant increased in urea and creatinine compared with control group ( P< 0.001) and significant decreased in TT4(P < 0.01) , TT3(P < 0.001) , fT4( P < 0.01) and fT3( P< 0.001) , whereas TSH values were not significantly altered .
Conclusions: Uremia is accompanied with endocrine disorders , due to impaired degradation of hormones , because of failed kidney functions and to the interference of the uremic environment with extra renal degradation or synthesis and secretion of certain hormones .
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| first_indexed | 2024-03-10T20:05:00Z |
| format | Article |
| id | doaj.art-ec01092398e14c71a477c0e0cb27001d |
| institution | Directory Open Access Journal |
| issn | 2219-9764 2617-8982 |
| language | English |
| last_indexed | 2024-03-10T20:05:00Z |
| publishDate | 2019-11-01 |
| publisher | College of medicine/ University of Diyala |
| record_format | Article |
| series | Diyala Journal of Medicine |
| spelling | doaj.art-ec01092398e14c71a477c0e0cb27001d2023-11-19T23:20:39ZengCollege of medicine/ University of DiyalaDiyala Journal of Medicine2219-97642617-89822019-11-0131Association Between Chronic Renal Failure and Thyroid HormoneHameed M Majeed Mazin Razooqi Mohammed Nabeel Khalid Mohamed Ali AL-Wandi Fatimah Kadhim Ibrahim Background: The idea of the study is to follow the relation between CR.E and thyroid hormones. Material and Methods: The levels of serum urea , creatinine ,total thyroxin (TT4) , Tri-iodothyronine (TT3) , free T4 (fT4) , freeT3 (fT3) and Thyrotropin (TSH) were measured in the serum of 80 Patients with varying grades of chronic renal failure (CRF) ; and 40 healthy individuals . They were divided into 3 groups as : Group 1 containing 40 healthy individuals as control group; Group 2 containing 40 Patients on conservative management ; and Group 3 containing 40 Patients on Regular haemodialysis therapy. Aim: The aim of the study was to investigate the association between chronic renal failure and thyroid function. Results: Groups 2 and 3 showed significant increased in urea and creatinine compared with control group ( P< 0.001) and significant decreased in TT4(P < 0.01) , TT3(P < 0.001) , fT4( P < 0.01) and fT3( P< 0.001) , whereas TSH values were not significantly altered . Conclusions: Uremia is accompanied with endocrine disorders , due to impaired degradation of hormones , because of failed kidney functions and to the interference of the uremic environment with extra renal degradation or synthesis and secretion of certain hormones . https://www.djm.uodiyala.edu.iq/index.php/djm/article/view/430chronic renal failure , thyroid hormones |
| spellingShingle | Hameed M Majeed Mazin Razooqi Mohammed Nabeel Khalid Mohamed Ali AL-Wandi Fatimah Kadhim Ibrahim Association Between Chronic Renal Failure and Thyroid Hormone Diyala Journal of Medicine chronic renal failure , thyroid hormones |
| title | Association Between Chronic Renal Failure and Thyroid Hormone |
| title_full | Association Between Chronic Renal Failure and Thyroid Hormone |
| title_fullStr | Association Between Chronic Renal Failure and Thyroid Hormone |
| title_full_unstemmed | Association Between Chronic Renal Failure and Thyroid Hormone |
| title_short | Association Between Chronic Renal Failure and Thyroid Hormone |
| title_sort | association between chronic renal failure and thyroid hormone |
| topic | chronic renal failure , thyroid hormones |
| url | https://www.djm.uodiyala.edu.iq/index.php/djm/article/view/430 |
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