Optimizing Single Agent Panitumumab Therapy in Pre-Treated Advanced Colorectal Cancer
PURPOSE: To improve the selection of advanced colorectal cancer patients to panitumumab by optimizing the assessment of RAS (KRAS-NRAS) mutations. EXPERIMENTAL DESIGN: Using a centralized pyrosequencing RAS assay, we analyzed the tumors of 94 patients, wild-type for KRAS mutations (codons 12 to 13)...
| Asıl Yazarlar: | , , , , , , , , , , , |
|---|---|
| Materyal Türü: | Makale |
| Dil: | English |
| Baskı/Yayın Bilgisi: |
Elsevier
2014-09-01
|
| Seri Bilgileri: | Neoplasia: An International Journal for Oncology Research |
| Online Erişim: | http://www.sciencedirect.com/science/article/pii/S1476558614001080 |