Expanding the Differential Diagnosis of the Painful Nail: A Case of an Onychopapilloma with Neuroma
Introduction: Onychopapilloma most commonly presents as longitudinal erythronychia, but diagnosis may be challenging in some cases due to varied clinical presentations. Most patients with onychopapillomas do not report associated pain but instead more commonly report functional interference. Case Re...
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| Format: | Article |
| Language: | English |
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Karger Publishers
2024-03-01
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| Series: | Case Reports in Dermatology |
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| Online Access: | https://beta.karger.com/Article/FullText/538087 |
| _version_ | 1827274940286500864 |
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| author | Jade Conway Cynthia M. Magro Shari R. Lipner |
| author_facet | Jade Conway Cynthia M. Magro Shari R. Lipner |
| author_sort | Jade Conway |
| collection | DOAJ |
| description | Introduction: Onychopapilloma most commonly presents as longitudinal erythronychia, but diagnosis may be challenging in some cases due to varied clinical presentations. Most patients with onychopapillomas do not report associated pain but instead more commonly report functional interference. Case Report: We present a case of a 74-year-old female with a 5-year history of splitting and lifting of the right thumbnail, accompanied by nail sensitivity and intermittent painful throbbing. Clinical examination was significant for a less than 1 mm red line with distal onycholysis. Love’s test and a cold test performed with ice pack were negative. X-ray of the right thumb was negative for erosion or exostosis. Nail biopsy was performed, and dermatopathology was consistent with onychopapilloma with a concomitant traumatic neuroma. Conclusion: We report a case of onychopapilloma with a concomitant traumatic neuroma. Subungual neuromas are extremely rare and have not previously been associated with onychopapilloma. Our case supports the expansion of the differential diagnosis for a painful nail and demonstrates the importance of diagnostic confirmation with biopsy and histopathology. |
| first_indexed | 2024-04-24T07:55:33Z |
| format | Article |
| id | doaj.art-ec077e158d9d496eb3a5f3f2e498f1d7 |
| institution | Directory Open Access Journal |
| issn | 1662-6567 |
| language | English |
| last_indexed | 2025-03-22T06:32:59Z |
| publishDate | 2024-03-01 |
| publisher | Karger Publishers |
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| series | Case Reports in Dermatology |
| spelling | doaj.art-ec077e158d9d496eb3a5f3f2e498f1d72024-04-25T06:31:59ZengKarger PublishersCase Reports in Dermatology1662-65672024-03-01161889310.1159/000538087538087Expanding the Differential Diagnosis of the Painful Nail: A Case of an Onychopapilloma with NeuromaJade Conway0Cynthia M. Magro1Shari R. Lipner2New York Medical College, Valhalla, NY, USADepartment of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USADepartment of Dermatology, Weill Cornell Medicine, New York, NY, USAIntroduction: Onychopapilloma most commonly presents as longitudinal erythronychia, but diagnosis may be challenging in some cases due to varied clinical presentations. Most patients with onychopapillomas do not report associated pain but instead more commonly report functional interference. Case Report: We present a case of a 74-year-old female with a 5-year history of splitting and lifting of the right thumbnail, accompanied by nail sensitivity and intermittent painful throbbing. Clinical examination was significant for a less than 1 mm red line with distal onycholysis. Love’s test and a cold test performed with ice pack were negative. X-ray of the right thumb was negative for erosion or exostosis. Nail biopsy was performed, and dermatopathology was consistent with onychopapilloma with a concomitant traumatic neuroma. Conclusion: We report a case of onychopapilloma with a concomitant traumatic neuroma. Subungual neuromas are extremely rare and have not previously been associated with onychopapilloma. Our case supports the expansion of the differential diagnosis for a painful nail and demonstrates the importance of diagnostic confirmation with biopsy and histopathology.https://beta.karger.com/Article/FullText/538087onychopapillomaneuromanailpain |
| spellingShingle | Jade Conway Cynthia M. Magro Shari R. Lipner Expanding the Differential Diagnosis of the Painful Nail: A Case of an Onychopapilloma with Neuroma Case Reports in Dermatology onychopapilloma neuroma nail pain |
| title | Expanding the Differential Diagnosis of the Painful Nail: A Case of an Onychopapilloma with Neuroma |
| title_full | Expanding the Differential Diagnosis of the Painful Nail: A Case of an Onychopapilloma with Neuroma |
| title_fullStr | Expanding the Differential Diagnosis of the Painful Nail: A Case of an Onychopapilloma with Neuroma |
| title_full_unstemmed | Expanding the Differential Diagnosis of the Painful Nail: A Case of an Onychopapilloma with Neuroma |
| title_short | Expanding the Differential Diagnosis of the Painful Nail: A Case of an Onychopapilloma with Neuroma |
| title_sort | expanding the differential diagnosis of the painful nail a case of an onychopapilloma with neuroma |
| topic | onychopapilloma neuroma nail pain |
| url | https://beta.karger.com/Article/FullText/538087 |
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