Identification of COVID-19 severity biomarkers based on feature selection on single-cell RNA-Seq data of CD8+ T cells

Identification of COVID-19 severity biomarkers based on feature selection on single-cell RNA-Seq data of CD8+ T cells

The global outbreak of the COVID-19 epidemic has become a major public health problem. COVID-19 virus infection triggers a complex immune response. CD8+ T cells, in particular, play an essential role in controlling the severity of the disease. However, the mechanism of the regulatory role of CD8+ T...

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Detalles Bibliográficos
Main Authors: Jian Lu, Mei Meng, XianChao Zhou, Shijian Ding, KaiYan Feng, Zhenbing Zeng, Tao Huang, Yu-Dong Cai
Formato: Artigo
Idioma:English
Publicado: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Genetics
Subjects:
COVID-19
severity
CD8+ T cell
single-cell
feature selection
Acceso en liña:https://www.frontiersin.org/articles/10.3389/fgene.2022.1053772/full

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