The telmisartan and amlodipine combination in the treatment of hypertension
The following review assesses socially significant disease - hypertension (AH) - and the problem of finding an effective antihypertensive therapy. Twynsta® drug (manufacturer Boehringer Ingelheim Pharma) - modern combined antihypertensive drug, which not only provides effective blood pressure contro...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
IP Morozov P.V.
2014-03-01
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| Series: | Системные гипертензии |
| Subjects: | |
| Online Access: | https://syst-hypertension.ru/2075-082X/article/viewFile/29014/pdf |
| _version_ | 1818287996153102336 |
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| author | G G Shehyan A A Yalymov A M Schikota V S Zadionchenko S I Varentsov |
| author_facet | G G Shehyan A A Yalymov A M Schikota V S Zadionchenko S I Varentsov |
| author_sort | G G Shehyan |
| collection | DOAJ |
| description | The following review assesses socially significant disease - hypertension (AH) - and the problem of finding an effective antihypertensive therapy. Twynsta® drug (manufacturer Boehringer Ingelheim Pharma) - modern combined antihypertensive drug, which not only provides effective blood pressure control, but also due to the protective effect has been proved for all target organs improves the life expectancy of patients with hypertension. The clinical studies show that combination of telmisartan and amlodipine provides additional benefits in the treatment of patients with metabolic syndrome (by improving the carbohydrate and lipid metabolism), patients with impaired renal function (by inducing the regression of proteinuria), as well as left ventricular hypertrophy (by causing regression of the latter). The recently completed studies have shown that telmisartan acts as a selective PPAR-receptor modulator.In the present review it is shown that Twynsta® represents modern combined antihypertensive drugs and has a clinically proven favorable efficacy and safety profile. |
| first_indexed | 2024-12-13T01:49:21Z |
| format | Article |
| id | doaj.art-ec0ca4500d154b2893c0e35f26bca55c |
| institution | Directory Open Access Journal |
| issn | 2075-082X 2542-2189 |
| language | Russian |
| last_indexed | 2024-12-13T01:49:21Z |
| publishDate | 2014-03-01 |
| publisher | IP Morozov P.V. |
| record_format | Article |
| series | Системные гипертензии |
| spelling | doaj.art-ec0ca4500d154b2893c0e35f26bca55c2022-12-22T00:03:34ZrusIP Morozov P.V.Системные гипертензии2075-082X2542-21892014-03-01111647226115The telmisartan and amlodipine combination in the treatment of hypertensionG G ShehyanA A YalymovA M SchikotaV S ZadionchenkoS I VarentsovThe following review assesses socially significant disease - hypertension (AH) - and the problem of finding an effective antihypertensive therapy. Twynsta® drug (manufacturer Boehringer Ingelheim Pharma) - modern combined antihypertensive drug, which not only provides effective blood pressure control, but also due to the protective effect has been proved for all target organs improves the life expectancy of patients with hypertension. The clinical studies show that combination of telmisartan and amlodipine provides additional benefits in the treatment of patients with metabolic syndrome (by improving the carbohydrate and lipid metabolism), patients with impaired renal function (by inducing the regression of proteinuria), as well as left ventricular hypertrophy (by causing regression of the latter). The recently completed studies have shown that telmisartan acts as a selective PPAR-receptor modulator.In the present review it is shown that Twynsta® represents modern combined antihypertensive drugs and has a clinically proven favorable efficacy and safety profile.https://syst-hypertension.ru/2075-082X/article/viewFile/29014/pdfarterial hypertensiontreatmentcombined antihypertensive drugstelmisartanamlodipineorgan effectefficiencysafety |
| spellingShingle | G G Shehyan A A Yalymov A M Schikota V S Zadionchenko S I Varentsov The telmisartan and amlodipine combination in the treatment of hypertension Системные гипертензии arterial hypertension treatment combined antihypertensive drugs telmisartan amlodipine organ effect efficiency safety |
| title | The telmisartan and amlodipine combination in the treatment of hypertension |
| title_full | The telmisartan and amlodipine combination in the treatment of hypertension |
| title_fullStr | The telmisartan and amlodipine combination in the treatment of hypertension |
| title_full_unstemmed | The telmisartan and amlodipine combination in the treatment of hypertension |
| title_short | The telmisartan and amlodipine combination in the treatment of hypertension |
| title_sort | telmisartan and amlodipine combination in the treatment of hypertension |
| topic | arterial hypertension treatment combined antihypertensive drugs telmisartan amlodipine organ effect efficiency safety |
| url | https://syst-hypertension.ru/2075-082X/article/viewFile/29014/pdf |
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