Metal Oxide Nanoparticles Against Bacterial Biofilms: Perspectives and Limitations
At present, there is an urgent need in medicine and industry to develop new approaches to eliminate bacterial biofilms. Considering the low efficiency of classical approaches to biofilm eradication and the growing problem of antibiotic resistance, the introduction of nanomaterials may be a promising...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-10-01
|
| Series: | Microorganisms |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-2607/8/10/1545 |
| _version_ | 1797551663839444992 |
|---|---|
| author | Liubov Shkodenko Ilia Kassirov Elena Koshel |
| author_facet | Liubov Shkodenko Ilia Kassirov Elena Koshel |
| author_sort | Liubov Shkodenko |
| collection | DOAJ |
| description | At present, there is an urgent need in medicine and industry to develop new approaches to eliminate bacterial biofilms. Considering the low efficiency of classical approaches to biofilm eradication and the growing problem of antibiotic resistance, the introduction of nanomaterials may be a promising solution. Outstanding antimicrobial properties have been demonstrated by nanoparticles (NPs) of metal oxides and their nanocomposites. The review presents a comparative analysis of antibiofilm properties of various metal oxide NPs (primarily, CuO, Fe<sub>3</sub>O<sub>4</sub>, TiO<sub>2</sub>, ZnO, MgO, and Al<sub>2</sub>O<sub>3</sub> NPs) and nanocomposites, as well as mechanisms of their effect on plankton bacteria cells and biofilms. The potential mutagenicity of metal oxide NPs and safety problems of their wide application are also discussed. |
| first_indexed | 2024-03-10T15:48:18Z |
| format | Article |
| id | doaj.art-ec182def162c4e5fa6d9798418fbffb7 |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-10T15:48:18Z |
| publishDate | 2020-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-ec182def162c4e5fa6d9798418fbffb72023-11-20T16:16:45ZengMDPI AGMicroorganisms2076-26072020-10-01810154510.3390/microorganisms8101545Metal Oxide Nanoparticles Against Bacterial Biofilms: Perspectives and LimitationsLiubov Shkodenko0Ilia Kassirov1Elena Koshel2Microbiology Lab of SCAMT Institute, ITMO University, Lomonosova st. 9, 191002 St. Petersburg, RussiaMicrobiology Lab of SCAMT Institute, ITMO University, Lomonosova st. 9, 191002 St. Petersburg, RussiaMicrobiology Lab of SCAMT Institute, ITMO University, Lomonosova st. 9, 191002 St. Petersburg, RussiaAt present, there is an urgent need in medicine and industry to develop new approaches to eliminate bacterial biofilms. Considering the low efficiency of classical approaches to biofilm eradication and the growing problem of antibiotic resistance, the introduction of nanomaterials may be a promising solution. Outstanding antimicrobial properties have been demonstrated by nanoparticles (NPs) of metal oxides and their nanocomposites. The review presents a comparative analysis of antibiofilm properties of various metal oxide NPs (primarily, CuO, Fe<sub>3</sub>O<sub>4</sub>, TiO<sub>2</sub>, ZnO, MgO, and Al<sub>2</sub>O<sub>3</sub> NPs) and nanocomposites, as well as mechanisms of their effect on plankton bacteria cells and biofilms. The potential mutagenicity of metal oxide NPs and safety problems of their wide application are also discussed.https://www.mdpi.com/2076-2607/8/10/1545metal oxide nanoparticlesnanocompositesbiofilmantibiofilm propertiesantibacterial propertiesmutagenicity |
| spellingShingle | Liubov Shkodenko Ilia Kassirov Elena Koshel Metal Oxide Nanoparticles Against Bacterial Biofilms: Perspectives and Limitations Microorganisms metal oxide nanoparticles nanocomposites biofilm antibiofilm properties antibacterial properties mutagenicity |
| title | Metal Oxide Nanoparticles Against Bacterial Biofilms: Perspectives and Limitations |
| title_full | Metal Oxide Nanoparticles Against Bacterial Biofilms: Perspectives and Limitations |
| title_fullStr | Metal Oxide Nanoparticles Against Bacterial Biofilms: Perspectives and Limitations |
| title_full_unstemmed | Metal Oxide Nanoparticles Against Bacterial Biofilms: Perspectives and Limitations |
| title_short | Metal Oxide Nanoparticles Against Bacterial Biofilms: Perspectives and Limitations |
| title_sort | metal oxide nanoparticles against bacterial biofilms perspectives and limitations |
| topic | metal oxide nanoparticles nanocomposites biofilm antibiofilm properties antibacterial properties mutagenicity |
| url | https://www.mdpi.com/2076-2607/8/10/1545 |
| work_keys_str_mv | AT liubovshkodenko metaloxidenanoparticlesagainstbacterialbiofilmsperspectivesandlimitations AT iliakassirov metaloxidenanoparticlesagainstbacterialbiofilmsperspectivesandlimitations AT elenakoshel metaloxidenanoparticlesagainstbacterialbiofilmsperspectivesandlimitations |