Mapping Quantitative Trait Loci Underlying Function-Valued Traits Using Functional Principal Component Analysis and Multi-Trait Mapping

Mapping Quantitative Trait Loci Underlying Function-Valued Traits Using Functional Principal Component Analysis and Multi-Trait Mapping

We previously proposed a simple regression-based method to map quantitative trait loci underlying function-valued phenotypes. In order to better handle the case of noisy phenotype measurements and accommodate the correlation structure among time points, we propose an alternative approach that mainta...

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Bibliographic Details
Main Authors: Il-Youp Kwak, Candace R. Moore, Edgar P. Spalding, Karl W. Broman
Format: Article
Language:English
Published: Oxford University Press 2016-01-01
Series:G3: Genes, Genomes, Genetics
Subjects:
QTL
function-valued traits
model selection
growth curves
multivariate analysis
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.115.024133

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