Potential Role of Sleep Deficiency in Inducing Immune Dysfunction
Sleep deficiency and insomnia deteriorate the quality of patients’ lives, yet the exact influence of these factors on the immune system has only begun to gain interest in recent years. Growing evidence shows that insomnia is a risk factor for numerous diseases, including common infections and autoim...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-09-01
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| Series: | Biomedicines |
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| Online Access: | https://www.mdpi.com/2227-9059/10/9/2159 |
| _version_ | 1797490907534065664 |
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| author | Kasper Kuna Krzysztof Szewczyk Agata Gabryelska Piotr Białasiewicz Marta Ditmer Dominik Strzelecki Marcin Sochal |
| author_facet | Kasper Kuna Krzysztof Szewczyk Agata Gabryelska Piotr Białasiewicz Marta Ditmer Dominik Strzelecki Marcin Sochal |
| author_sort | Kasper Kuna |
| collection | DOAJ |
| description | Sleep deficiency and insomnia deteriorate the quality of patients’ lives, yet the exact influence of these factors on the immune system has only begun to gain interest in recent years. Growing evidence shows that insomnia is a risk factor for numerous diseases, including common infections and autoimmune diseases. Levels of inflammatory markers also seem to be abnormal in sleep deficient individuals, which may lead to low-grade inflammation. The interpretation of studies is difficult due to the equivocal term “sleep disturbances,” as well as due to the various criteria used in studies. This narrative review aims to summarize the available knowledge regarding the bidirectional influence of the immune system and sleep disturbances. |
| first_indexed | 2024-03-10T00:39:46Z |
| format | Article |
| id | doaj.art-ec1910835f3044f48bd1306df1d84e5a |
| institution | Directory Open Access Journal |
| issn | 2227-9059 |
| language | English |
| last_indexed | 2024-03-10T00:39:46Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj.art-ec1910835f3044f48bd1306df1d84e5a2023-11-23T15:10:05ZengMDPI AGBiomedicines2227-90592022-09-01109215910.3390/biomedicines10092159Potential Role of Sleep Deficiency in Inducing Immune DysfunctionKasper Kuna0Krzysztof Szewczyk1Agata Gabryelska2Piotr Białasiewicz3Marta Ditmer4Dominik Strzelecki5Marcin Sochal6Department of Sleep Medicine and Metabolic Disorders, Medical University of Lodz, 92-215 Lodz, PolandDepartment of Sleep Medicine and Metabolic Disorders, Medical University of Lodz, 92-215 Lodz, PolandDepartment of Sleep Medicine and Metabolic Disorders, Medical University of Lodz, 92-215 Lodz, PolandDepartment of Sleep Medicine and Metabolic Disorders, Medical University of Lodz, 92-215 Lodz, PolandDepartment of Sleep Medicine and Metabolic Disorders, Medical University of Lodz, 92-215 Lodz, PolandDepartment of Affective and Psychotic Disorders, Medical University of Lodz, 92-213 Lodz, PolandDepartment of Sleep Medicine and Metabolic Disorders, Medical University of Lodz, 92-215 Lodz, PolandSleep deficiency and insomnia deteriorate the quality of patients’ lives, yet the exact influence of these factors on the immune system has only begun to gain interest in recent years. Growing evidence shows that insomnia is a risk factor for numerous diseases, including common infections and autoimmune diseases. Levels of inflammatory markers also seem to be abnormal in sleep deficient individuals, which may lead to low-grade inflammation. The interpretation of studies is difficult due to the equivocal term “sleep disturbances,” as well as due to the various criteria used in studies. This narrative review aims to summarize the available knowledge regarding the bidirectional influence of the immune system and sleep disturbances.https://www.mdpi.com/2227-9059/10/9/2159immune systemvaccinationautoantibodiespsychoneuroimmunologysleep deficiencyinsomnia |
| spellingShingle | Kasper Kuna Krzysztof Szewczyk Agata Gabryelska Piotr Białasiewicz Marta Ditmer Dominik Strzelecki Marcin Sochal Potential Role of Sleep Deficiency in Inducing Immune Dysfunction Biomedicines immune system vaccination autoantibodies psychoneuroimmunology sleep deficiency insomnia |
| title | Potential Role of Sleep Deficiency in Inducing Immune Dysfunction |
| title_full | Potential Role of Sleep Deficiency in Inducing Immune Dysfunction |
| title_fullStr | Potential Role of Sleep Deficiency in Inducing Immune Dysfunction |
| title_full_unstemmed | Potential Role of Sleep Deficiency in Inducing Immune Dysfunction |
| title_short | Potential Role of Sleep Deficiency in Inducing Immune Dysfunction |
| title_sort | potential role of sleep deficiency in inducing immune dysfunction |
| topic | immune system vaccination autoantibodies psychoneuroimmunology sleep deficiency insomnia |
| url | https://www.mdpi.com/2227-9059/10/9/2159 |
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