Immunomodulatory effects of β-defensin 2 on macrophages induced immuno-upregulation and their antitumor function in breast cancer

Immunomodulatory effects of β-defensin 2 on macrophages induced immuno-upregulation and their antitumor function in breast cancer

Abstract Background Macrophages are mononuclear CD34+ antigen-presenting cells of defense mechanism and play dual roles in tumor burden. The immunomodulatory and their antitumor function of β-defensin 2 is still unclear, despite the accumulating evidence of the response in infection. So, the aim of...

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Bibliographic Details
Main Authors: Sonam Agarwal, Anita Chauhan, Khushwant Singh, Kunal Kumar, Rupinder Kaur, Marilyn Masih, Pramod Kumar Gautam
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Immunology
Subjects:
Macrophages
β-defensin 2
Cytokine profiling
Anti-tumor function
Oxidative stress
Online Access:https://doi.org/10.1186/s12865-022-00527-y

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