Non-imidazole-based histamine H3 receptor antagonists with anticonvulsant activity in different seizure models in male adult rats

Non-imidazole-based histamine H3 receptor antagonists with anticonvulsant activity in different seizure models in male adult rats

Bassem Sadek,1 Ali Saad,1 Gniewomir Latacz,2 Kamil Kuder,2 Agnieszka Olejarz,2 Tadeusz Karcz,2 Holger Stark,3 Katarzyna Kieć-Kononowicz2 1Department of Pharmacology and Therapeutics, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates; 2Department...

Full description

Bibliographic Details
Main Authors:	Sadek B, Saad A, Latacz G, Kuder K, Olejarz A, Karcz T, Stark H, Kiec´-Kononowicz K
Format:	Article
Language:	English
Published:	Dove Medical Press 2016-11-01
Series:	Drug Design, Development and Therapy
Subjects:	Histamine H3 receptors Antagonists Anticonvulsant R-()-methyl-histamine Pyrilamine Zolantidine
Online Access:	https://www.dovepress.com/non-imidazole-based-histamine-h3-receptor-antagonists-with-anticonvuls-peer-reviewed-article-DDDT

Similar Items

Studies on Anticonvulsant Effects of Novel Histamine H3R Antagonists in Electrically and Chemically Induced Seizures in Rats
by: Alaa Alachkar, et al.
Published: (2018-10-01)

Anticonvulsant effects of isomeric nonimidazole histamine H3 receptor antagonists
by: Sadek B, et al.
Published: (2016-11-01)

The Effects of Histaminergic Agents in the Nucleus ccumbens of Rats in the Elevated Plus-Maze Test of Anxiety
by: Ameneh Rezayof, et al.
Published: (2010-05-01)

The effects of histaminergic agents in the nucleus accumbens of rats in the elevated plus-maze test of anxiety.
by: Mohammad-Reza Zarrindast, et al.
Published: (2010-03-01)

Suppression of wheal and flare in histamine test by the main H1 antihistamines commercialized in Brazil
by: Helena Maciel-Guerra, et al.
Published: (2018-03-01)

The Effects of Histaminergic Agents in the Nucleus Accumbens of Rats in the Elevated Plus-Maze Test of Anxiety
by: Mohammad-Reza Zarrindast, et al.
Published: (2010-11-01)

Structures 4-n-propyl Piperazines as Non-Imidazole Histamine H3 Antagonists
by: Andrzej Olczak, et al.
Published: (2021-11-01)

In search of potent histamine-3 receptor antagonists
by: Sankar Chatterjee
Published: (2015-04-01)

Histamine H3 receptor antagonist E177 attenuates amnesia induced by dizocilpine without modulation of anxiety-like behaviors in rats
by: Alachkar A, et al.
Published: (2019-02-01)

Simultaneous Blockade of Histamine H<sub>3</sub> Receptors and Inhibition of Acetylcholine Esterase Alleviate Autistic-Like Behaviors in BTBR T+ tf/J Mouse Model of Autism
by: Nermin Eissa, et al.
Published: (2020-08-01)

The Histamine H3 Receptor Antagonist DL77 Ameliorates MK801-Induced Memory Deficits in Rats
by: Nermin Eissa, et al.
Published: (2018-02-01)

Targeted therapy with histamine antagonists - New challenges to fight with breast cancer
by: Piotr Jan Więsyk, et al.
Published: (2022-11-01)

Combination of H1 and H2 Histamine Receptor Antagonists: Current Knowledge and Perspectives of a Classic Treatment Strategy
by: Erwen Kou, et al.
Published: (2024-01-01)

Low-Histamine Diets: Is the Exclusion of Foods Justified by Their Histamine Content?
by: Sònia Sánchez-Pérez, et al.
Published: (2021-04-01)

The Histamine H3 Receptor Antagonist E159 Reverses Memory Deficits Induced by Dizocilpine in Passive Avoidance and Novel Object Recognition Paradigm in Rats
by: Alaa Alachkar, et al.
Published: (2017-10-01)

Dual Target Ligands with 4-<i>tert</i>-Butylphenoxy Scaffold as Histamine H<sub>3</sub> Receptor Antagonists and Monoamine Oxidase B Inhibitors
by: Dorota Łażewska, et al.
Published: (2020-05-01)

Effects of administration of histamine and its H1, H2, and H3 receptor antagonists into the primary somatosensory cortex on inflammatory pain in rats
by: Esmaeal Tamaddonfard, et al.
Published: (2014-01-01)

Trisubstituted 1,3,5-Triazines as Histamine H<sub>4</sub> Receptor Antagonists with Promising Activity In Vivo
by: Agnieszka Olejarz-Maciej, et al.
Published: (2023-05-01)

Supression of histamine induced permeability of endothelium via nitric oxide.
by: Abdullah, Muhammad Nazrul Hakim, et al.
Published: (2010)

Histamine Produced by Gram-Negative Bacteria Impairs Neutrophil’s Antimicrobial Response by Engaging the Histamine 2 Receptor
by: Karim Dib, et al.
Published: (2022-07-01)

Effects of Histamine Receptor Antagonist Cetirizine on Orthodontic Tooth Movement
by: Gregor Sperl, et al.
Published: (2020-12-01)

Identification of histaminic (H1-type) receptors in small intestine of broilers by application of histamine and some of its agonists and antagonists
by: Mujezinović Indira, et al.
Published: (2010-01-01)

Discovery of Potential, Dual-Active Histamine H<sub>3</sub> Receptor Ligands with Combined Antioxidant Properties
by: Kamil J. Kuder, et al.
Published: (2021-04-01)

QSAR and Molecular Docking Studies on Non-Imidazole-Based Histamine H3 Receptor Antagonists
by: Maryam Hamzeh-Mivehroud, et al.
Published: (2020-06-01)

Effects of loratadine, a histamine H1 receptor antagonist, on the skeletal system of young male rats
by: Folwarczna J, et al.
Published: (2019-09-01)

Development and Characterization of a Diamine Oxidase-Based Histamine Biosensor
by: Ching, Mai Keow
Published: (2006)

Histamine Intolerance: The Current State of the Art
by: Oriol Comas-Basté, et al.
Published: (2020-08-01)

Determination of histamine and identification of histamine-producing bacteria in frozen Longtail tuna (Thunnus tonggol)
by: V Koohdar, et al.
Published: (2012-05-01)

The Dual-Active Histamine H<sub>3</sub> Receptor Antagonist and Acetylcholine Esterase Inhibitor E100 Alleviates Autistic-Like Behaviors and Oxidative Stress in Valproic Acid Induced Autism in Mice
by: Nermin Eissa, et al.
Published: (2020-06-01)

Improved survival in several cancers with use of H1-antihistamines desloratadine and loratadine
by: Ildikó Fritz, et al.
Published: (2021-04-01)

Novel Insight of Histamine and Its Receptor Ligands in Glaucoma and Retina Neuroprotection
by: Silvia Sgambellone, et al.
Published: (2021-08-01)

Histamina, receptores de histamina e anti-histamínicos: novos conceitos Histamine, histamine receptors and antihistamines: new concepts
by: Paulo Ricardo Criado, et al.
Published: (2010-04-01)

Histamine Intolerance—The More We Know the Less We Know. A Review
by: Martin Hrubisko, et al.
Published: (2021-06-01)

Antagonism of Histamine H3 receptors Alleviates Pentylenetetrazole-Induced Kindling and Associated Memory Deficits by Mitigating Oxidative Stress, Central Neurotransmitters, and c-Fos Protein Expression in Rats
by: Alaa Alachkar, et al.
Published: (2020-03-01)

The Role of Histamine and Histamine Receptors in Mast Cell-Mediated Allergy and Inflammation: The Hunt for New Therapeutic Targets
by: Elden Berla Thangam, et al.
Published: (2018-08-01)

TRPV1 and TRPA1 Channels Are Both Involved Downstream of Histamine-Induced Itch
by: Jenny Wilzopolski, et al.
Published: (2021-08-01)

Histamine and histamine receptors: Roles in major depressive disorder
by: Hong Qian, et al.
Published: (2022-09-01)

Role of Histamine and Related Signaling in Kaposi’s Sarcoma-Associated Herpesvirus Pathogenesis and Oncogenesis
by: Jungang Chen, et al.
Published: (2023-04-01)

The Histamine H<sub>4</sub> Receptor Participates in the Neuropathic Pain-Relieving Activity of the Histamine H<sub>3</sub> Receptor Antagonist GSK189254
by: Vittoria Borgonetti, et al.
Published: (2022-11-01)

New semisynthetic andrographolide and 14-Deoxy-11, 12-didehydroandrographolide derivatives with anticancer, anti-histamine and nitric oxide inhibitory activities
by: Jeyaraj Asirvatham, Ethel Jeyaseela
Published: (2016)