Coat proteins of necroviruses target 14-3-3a to subvert MAPKKKα-mediated antiviral immunity in plants
MAPK cascades play an important role in innate immunity. Here, the authors show that that beet black scorch virus activates MAPK signaling in Nicotiana benthamiana and the viral coat protein counteracts MAPK-mediated defence by competitively binding to a MAPKKKα interactor.
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-02-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-28395-5 |
| _version_ | 1818683118213660672 |
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| author | Zongyu Gao Dingliang Zhang Xiaoling Wang Xin Zhang Zhiyan Wen Qianshen Zhang Dawei Li Savithramma P. Dinesh-Kumar Yongliang Zhang |
| author_facet | Zongyu Gao Dingliang Zhang Xiaoling Wang Xin Zhang Zhiyan Wen Qianshen Zhang Dawei Li Savithramma P. Dinesh-Kumar Yongliang Zhang |
| author_sort | Zongyu Gao |
| collection | DOAJ |
| description | MAPK cascades play an important role in innate immunity. Here, the authors show that that beet black scorch virus activates MAPK signaling in Nicotiana benthamiana and the viral coat protein counteracts MAPK-mediated defence by competitively binding to a MAPKKKα interactor. |
| first_indexed | 2024-12-17T10:29:39Z |
| format | Article |
| id | doaj.art-ec2739e13f22476e9f585e81c79f90db |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-17T10:29:39Z |
| publishDate | 2022-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-ec2739e13f22476e9f585e81c79f90db2022-12-21T21:52:33ZengNature PortfolioNature Communications2041-17232022-02-0113112010.1038/s41467-022-28395-5Coat proteins of necroviruses target 14-3-3a to subvert MAPKKKα-mediated antiviral immunity in plantsZongyu Gao0Dingliang Zhang1Xiaoling Wang2Xin Zhang3Zhiyan Wen4Qianshen Zhang5Dawei Li6Savithramma P. Dinesh-Kumar7Yongliang Zhang8State Key Laboratory of Agro-Biotechnology and Ministry of Agriculture Key Laboratory of Soil Microbiology, College of Biological Sciences, China Agricultural UniversityState Key Laboratory of Agro-Biotechnology and Ministry of Agriculture Key Laboratory of Soil Microbiology, College of Biological Sciences, China Agricultural UniversityState Key Laboratory of Agro-Biotechnology and Ministry of Agriculture Key Laboratory of Soil Microbiology, College of Biological Sciences, China Agricultural UniversityState Key Laboratory of Agro-Biotechnology and Ministry of Agriculture Key Laboratory of Soil Microbiology, College of Biological Sciences, China Agricultural UniversityState Key Laboratory of Agro-Biotechnology and Ministry of Agriculture Key Laboratory of Soil Microbiology, College of Biological Sciences, China Agricultural UniversityState Key Laboratory of Agro-Biotechnology and Ministry of Agriculture Key Laboratory of Soil Microbiology, College of Biological Sciences, China Agricultural UniversityState Key Laboratory of Agro-Biotechnology and Ministry of Agriculture Key Laboratory of Soil Microbiology, College of Biological Sciences, China Agricultural UniversityDepartment of Plant Biology and The Genome Center, College of Biological Sciences, University of California, DavisState Key Laboratory of Agro-Biotechnology and Ministry of Agriculture Key Laboratory of Soil Microbiology, College of Biological Sciences, China Agricultural UniversityMAPK cascades play an important role in innate immunity. Here, the authors show that that beet black scorch virus activates MAPK signaling in Nicotiana benthamiana and the viral coat protein counteracts MAPK-mediated defence by competitively binding to a MAPKKKα interactor.https://doi.org/10.1038/s41467-022-28395-5 |
| spellingShingle | Zongyu Gao Dingliang Zhang Xiaoling Wang Xin Zhang Zhiyan Wen Qianshen Zhang Dawei Li Savithramma P. Dinesh-Kumar Yongliang Zhang Coat proteins of necroviruses target 14-3-3a to subvert MAPKKKα-mediated antiviral immunity in plants Nature Communications |
| title | Coat proteins of necroviruses target 14-3-3a to subvert MAPKKKα-mediated antiviral immunity in plants |
| title_full | Coat proteins of necroviruses target 14-3-3a to subvert MAPKKKα-mediated antiviral immunity in plants |
| title_fullStr | Coat proteins of necroviruses target 14-3-3a to subvert MAPKKKα-mediated antiviral immunity in plants |
| title_full_unstemmed | Coat proteins of necroviruses target 14-3-3a to subvert MAPKKKα-mediated antiviral immunity in plants |
| title_short | Coat proteins of necroviruses target 14-3-3a to subvert MAPKKKα-mediated antiviral immunity in plants |
| title_sort | coat proteins of necroviruses target 14 3 3a to subvert mapkkkα mediated antiviral immunity in plants |
| url | https://doi.org/10.1038/s41467-022-28395-5 |
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