Characterization of a new CCCTC-binding factor binding site as a dual regulator of Epstein-Barr virus latent infection.

Distinct viral gene expression characterizes Epstein-Barr virus (EBV) infection in EBV-producing marmoset B-cell (B95-8) and EBV-associated gastric carcinoma (SNU719) cell lines. CCCTC-binding factor (CTCF) is a structural chromatin factor that coordinates chromatin interactions in the EBV genome. C...

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Main Authors: Sun Hee Lee, Kyoung-Dong Kim, Miyeon Cho, Sora Huh, Seong Ho An, Donghyun Seo, Kyuhyun Kang, Minhee Lee, Hideki Tanizawa, Inuk Jung, Hyosun Cho, Hyojeung Kang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1011078