A Comparison of the Therapeutic Efficacy of Conventional and Modern Oximes Against Supralethal Doses of Highly Toxic Organophosphates in Mice
1. The therapeutic efficacy of various oximes (pralidoxime, obidoxime, methoxime, HI-6, HLö-7, BI-6) against supralethal nerve agent poisoning (soman, sarin, cyclosin) in mice was tested. 2. New oxime BI-6, synthesized in our laboratory, is significantly more efficacious than conventional oximes but...
Κύριος συγγραφέας: | Jiří Kassa |
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Μορφή: | Άρθρο |
Γλώσσα: | English |
Έκδοση: |
Karolinum Press
1998-01-01
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Σειρά: | Acta Medica |
Θέματα: | |
Διαθέσιμο Online: | https://actamedica.lfhk.cuni.cz/41/1/0019/ |
Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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A Comparison of the Potency of the Oxime HLö-7 and Currently Used Oximes (HI-6, Pralidoxime, Obidoxime) to Reactivate Nerve Agent-Inhibited Rat Brain Acetylcholinesterase by in vitro Methods
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Έκδοση: (2005-01-01) -
The Influence of Oxime Selection on the Efficacy of Antidotal Treatment of Soman-Poisoned Rats
ανά: Jiří Kassa, κ.ά.
Έκδοση: (2002-01-01) -
FDA-Approved Oximes and Their Significance in Medicinal Chemistry
ανά: Jyothi Dhuguru, κ.ά.
Έκδοση: (2022-01-01) -
The Experimental Oxime K027—A Promising Protector From Organophosphate Pesticide Poisoning. A Review Comparing K027, K048, Pralidoxime, and Obidoxime
ανά: Dietrich E. Lorke, κ.ά.
Έκδοση: (2019-05-01) -
The Influence of Anticholinergic Drug Selection on the Effectiveness of Oximes Against Soman-Induced Supralethal Poisoning in Mice
ανά: Jiří Kassa
Έκδοση: (2001-01-01)