Blood Flow Analysis of the Great Saphenous Vein in the Su-Pine Position in Clinical Manifestations of Varicose Veins of Different Severities: Application of Phase-Contrast Magnetic Resonance Imaging Data
The progression of clinical manifestations of lower-limb varicose veins remains unclear. This study investigated changes in lower-limb venous blood flow using phase-contrast magnetic resonance angiography. Data were collected on veins from 141 legs. We compared legs with and without varicose veins a...
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MDPI AG
2022-01-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/12/1/118 |
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| author | Yuan-Hsi Tseng Chien-Wei Chen Min-Yi Wong Teng-Yao Yang Yu-Hui Lin Bor-Shyh Lin Yao-Kuang Huang |
| author_facet | Yuan-Hsi Tseng Chien-Wei Chen Min-Yi Wong Teng-Yao Yang Yu-Hui Lin Bor-Shyh Lin Yao-Kuang Huang |
| author_sort | Yuan-Hsi Tseng |
| collection | DOAJ |
| description | The progression of clinical manifestations of lower-limb varicose veins remains unclear. This study investigated changes in lower-limb venous blood flow using phase-contrast magnetic resonance angiography. Data were collected on veins from 141 legs. We compared legs with and without varicose veins and related symptoms and examined varying levels of varicose vein symptom severity. Legs without varicose veins exhibited a lower absolute stroke volume (ASV, <i>p</i> < 0.01) and mean flux (MF, <i>p</i> = 0.03) for the great saphenous vein (GSV) compared with legs with symptomatic varicose veins. Legs with asymptomatic varicose veins exhibited lower MF for the GSV (<i>p</i> = 0.02) compared with legs with symptomatic varicose veins. Among legs with varicose veins, asymptomatic legs exhibited lower ASV (<i>p</i> = 0.03) and MF (<i>p</i> = 0.046) for the GSV compared with legs that exhibited skin changes or ulcers; however, no significant differences were observed between legs presenting with discomfort or edema and legs with skin changes or ulcers, and between legs presenting with discomfort or edema and asymptomatic legs. In conclusion, in the supine position, increased blood flow rate and blood flow volume in the GSV were associated with symptomatic varicose veins and increased symptom severity. |
| first_indexed | 2024-03-10T01:38:56Z |
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| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T01:38:56Z |
| publishDate | 2022-01-01 |
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| series | Diagnostics |
| spelling | doaj.art-ec2cbfcc52e148cc826033b13526dffc2023-11-23T13:28:33ZengMDPI AGDiagnostics2075-44182022-01-0112111810.3390/diagnostics12010118Blood Flow Analysis of the Great Saphenous Vein in the Su-Pine Position in Clinical Manifestations of Varicose Veins of Different Severities: Application of Phase-Contrast Magnetic Resonance Imaging DataYuan-Hsi Tseng0Chien-Wei Chen1Min-Yi Wong2Teng-Yao Yang3Yu-Hui Lin4Bor-Shyh Lin5Yao-Kuang Huang6Division of Thoracic and Cardiovascular Surgery, Chiayi Chang Gung Memorial Hospital, College of Medicine, Chia-Yi and Chang Gung University, Taoyuan 33302, TaiwanDepartment of Diagnostic Radiology, Chiayi Chang Gung Memorial Hospital, College of Medicine, Chia-Yi and Chang Gung University, Taoyuan 33302, TaiwanDivision of Thoracic and Cardiovascular Surgery, Chiayi Chang Gung Memorial Hospital, College of Medicine, Chia-Yi and Chang Gung University, Taoyuan 33302, TaiwanDepartment of Cardiology, Chiayi Chang Gung Memorial Hospital, College of Medicine, Chia-Yi and Chang Gung University, Taoyuan 33302, TaiwanDivision of Thoracic and Cardiovascular Surgery, Chiayi Chang Gung Memorial Hospital, College of Medicine, Chia-Yi and Chang Gung University, Taoyuan 33302, TaiwanInstitute of Imaging and Biomedical Photonics, National Chiao Tung University, Tainan 300, TaiwanDivision of Thoracic and Cardiovascular Surgery, Chiayi Chang Gung Memorial Hospital, College of Medicine, Chia-Yi and Chang Gung University, Taoyuan 33302, TaiwanThe progression of clinical manifestations of lower-limb varicose veins remains unclear. This study investigated changes in lower-limb venous blood flow using phase-contrast magnetic resonance angiography. Data were collected on veins from 141 legs. We compared legs with and without varicose veins and related symptoms and examined varying levels of varicose vein symptom severity. Legs without varicose veins exhibited a lower absolute stroke volume (ASV, <i>p</i> < 0.01) and mean flux (MF, <i>p</i> = 0.03) for the great saphenous vein (GSV) compared with legs with symptomatic varicose veins. Legs with asymptomatic varicose veins exhibited lower MF for the GSV (<i>p</i> = 0.02) compared with legs with symptomatic varicose veins. Among legs with varicose veins, asymptomatic legs exhibited lower ASV (<i>p</i> = 0.03) and MF (<i>p</i> = 0.046) for the GSV compared with legs that exhibited skin changes or ulcers; however, no significant differences were observed between legs presenting with discomfort or edema and legs with skin changes or ulcers, and between legs presenting with discomfort or edema and asymptomatic legs. In conclusion, in the supine position, increased blood flow rate and blood flow volume in the GSV were associated with symptomatic varicose veins and increased symptom severity.https://www.mdpi.com/2075-4418/12/1/118magnetic resonance imagingmagnetic resonance venographynon-contrast venographyphase-contrast magnetic resonance imagingquantitative flowvaricose vein |
| spellingShingle | Yuan-Hsi Tseng Chien-Wei Chen Min-Yi Wong Teng-Yao Yang Yu-Hui Lin Bor-Shyh Lin Yao-Kuang Huang Blood Flow Analysis of the Great Saphenous Vein in the Su-Pine Position in Clinical Manifestations of Varicose Veins of Different Severities: Application of Phase-Contrast Magnetic Resonance Imaging Data Diagnostics magnetic resonance imaging magnetic resonance venography non-contrast venography phase-contrast magnetic resonance imaging quantitative flow varicose vein |
| title | Blood Flow Analysis of the Great Saphenous Vein in the Su-Pine Position in Clinical Manifestations of Varicose Veins of Different Severities: Application of Phase-Contrast Magnetic Resonance Imaging Data |
| title_full | Blood Flow Analysis of the Great Saphenous Vein in the Su-Pine Position in Clinical Manifestations of Varicose Veins of Different Severities: Application of Phase-Contrast Magnetic Resonance Imaging Data |
| title_fullStr | Blood Flow Analysis of the Great Saphenous Vein in the Su-Pine Position in Clinical Manifestations of Varicose Veins of Different Severities: Application of Phase-Contrast Magnetic Resonance Imaging Data |
| title_full_unstemmed | Blood Flow Analysis of the Great Saphenous Vein in the Su-Pine Position in Clinical Manifestations of Varicose Veins of Different Severities: Application of Phase-Contrast Magnetic Resonance Imaging Data |
| title_short | Blood Flow Analysis of the Great Saphenous Vein in the Su-Pine Position in Clinical Manifestations of Varicose Veins of Different Severities: Application of Phase-Contrast Magnetic Resonance Imaging Data |
| title_sort | blood flow analysis of the great saphenous vein in the su pine position in clinical manifestations of varicose veins of different severities application of phase contrast magnetic resonance imaging data |
| topic | magnetic resonance imaging magnetic resonance venography non-contrast venography phase-contrast magnetic resonance imaging quantitative flow varicose vein |
| url | https://www.mdpi.com/2075-4418/12/1/118 |
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