Design of a Multi-Epitopes Based Chimeric Vaccine against <i>Enterobacter cloacae</i> Using Pan-Genome and Reverse Vaccinology Approaches

Design of a Multi-Epitopes Based Chimeric Vaccine against <i>Enterobacter cloacae</i> Using Pan-Genome and Reverse Vaccinology Approaches

<i>Enterobacter cloacae</i> (EC) is a significant emerging pathogen that is occasionally associated with lung infection, surgical site infection, urinary infection, sepsis, and outbreaks in neonatal intensive care units. In light of the fact that there is currently no approved vaccine or...

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Bibliographic Details
Main Authors: Wafa Abdullah I. Al-Megrin, Alaa Karkashan, Abdullah M. Alnuqaydan, Faris F. Aba Alkhayl, Faris Alrumaihi, Ahmad Almatroudi, Khaled S. Allemailem
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Vaccines
Subjects:
<i>Enterobacter cloaca</i>
pangenome subtractive proteomics
immunoinformatic
molecular docking
molecular dynamic simulations
binding free energies
Online Access:https://www.mdpi.com/2076-393X/10/6/886

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