Dataset of allele and genotype frequencies of the three functionally significant polymorphisms of the MMP genes in Russian patients with primary open-angle glaucoma, essential hypertension and peptic ulcer
Data on the allele and genotype frequencies of the three functionally significant single nucleotide polymorphisms (SNPs) of the matrix metalloproteinases (MMP) genes (rs1799750 MMP1, rs3918242 and rs17576 MMP9) in Russian patients with primary open-angle glaucoma (POAG), essential hypertension (EH)...
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Format: | Article |
Language: | English |
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Elsevier
2020-08-01
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Series: | Data in Brief |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S2352340920308982 |
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author | Oksana Minyaylo Dina Starikova Maria Moskalenko Irina Ponomarenko Evgeny Reshetnikov Volodymyr Dvornyk Mikhail Churnosov |
author_facet | Oksana Minyaylo Dina Starikova Maria Moskalenko Irina Ponomarenko Evgeny Reshetnikov Volodymyr Dvornyk Mikhail Churnosov |
author_sort | Oksana Minyaylo |
collection | DOAJ |
description | Data on the allele and genotype frequencies of the three functionally significant single nucleotide polymorphisms (SNPs) of the matrix metalloproteinases (MMP) genes (rs1799750 MMP1, rs3918242 and rs17576 MMP9) in Russian patients with primary open-angle glaucoma (POAG), essential hypertension (EH) and peptic ulcer (PU) are presented. Association studies identified these SNPs as possible significant markers associated with many multifactorial disorders, including POAG, EH, and PU. The frequencies of alleles and genotypes of the three SNPs in Russian patients with POAG, EH, and PU were presented separately for the entire study sample, females, and males, respectively. The data can be used as a reference for the Russian population. |
first_indexed | 2024-12-21T12:04:15Z |
format | Article |
id | doaj.art-ec309ceb541b465c80ffc3c7fbb616ff |
institution | Directory Open Access Journal |
issn | 2352-3409 |
language | English |
last_indexed | 2024-12-21T12:04:15Z |
publishDate | 2020-08-01 |
publisher | Elsevier |
record_format | Article |
series | Data in Brief |
spelling | doaj.art-ec309ceb541b465c80ffc3c7fbb616ff2022-12-21T19:04:45ZengElsevierData in Brief2352-34092020-08-0131106004Dataset of allele and genotype frequencies of the three functionally significant polymorphisms of the MMP genes in Russian patients with primary open-angle glaucoma, essential hypertension and peptic ulcerOksana Minyaylo0Dina Starikova1Maria Moskalenko2Irina Ponomarenko3Evgeny Reshetnikov4Volodymyr Dvornyk5Mikhail Churnosov6Department of Medical Biological Disciplines, Belgorod State University, Belgorod 308015, RussiaDepartment of Medical Biological Disciplines, Belgorod State University, Belgorod 308015, RussiaDepartment of Medical Biological Disciplines, Belgorod State University, Belgorod 308015, RussiaDepartment of Medical Biological Disciplines, Belgorod State University, Belgorod 308015, RussiaDepartment of Medical Biological Disciplines, Belgorod State University, Belgorod 308015, Russia; Corresponding author.Department of Life Sciences, College of Science and General Studies, Alfaisal University, Riyadh 11533, Saudi ArabiaDepartment of Medical Biological Disciplines, Belgorod State University, Belgorod 308015, RussiaData on the allele and genotype frequencies of the three functionally significant single nucleotide polymorphisms (SNPs) of the matrix metalloproteinases (MMP) genes (rs1799750 MMP1, rs3918242 and rs17576 MMP9) in Russian patients with primary open-angle glaucoma (POAG), essential hypertension (EH) and peptic ulcer (PU) are presented. Association studies identified these SNPs as possible significant markers associated with many multifactorial disorders, including POAG, EH, and PU. The frequencies of alleles and genotypes of the three SNPs in Russian patients with POAG, EH, and PU were presented separately for the entire study sample, females, and males, respectively. The data can be used as a reference for the Russian population.http://www.sciencedirect.com/science/article/pii/S2352340920308982Single nucleotide polymorphismPrimary open-angle glaucomaEssential hypertensionPeptic ulcerMMP |
spellingShingle | Oksana Minyaylo Dina Starikova Maria Moskalenko Irina Ponomarenko Evgeny Reshetnikov Volodymyr Dvornyk Mikhail Churnosov Dataset of allele and genotype frequencies of the three functionally significant polymorphisms of the MMP genes in Russian patients with primary open-angle glaucoma, essential hypertension and peptic ulcer Data in Brief Single nucleotide polymorphism Primary open-angle glaucoma Essential hypertension Peptic ulcer MMP |
title | Dataset of allele and genotype frequencies of the three functionally significant polymorphisms of the MMP genes in Russian patients with primary open-angle glaucoma, essential hypertension and peptic ulcer |
title_full | Dataset of allele and genotype frequencies of the three functionally significant polymorphisms of the MMP genes in Russian patients with primary open-angle glaucoma, essential hypertension and peptic ulcer |
title_fullStr | Dataset of allele and genotype frequencies of the three functionally significant polymorphisms of the MMP genes in Russian patients with primary open-angle glaucoma, essential hypertension and peptic ulcer |
title_full_unstemmed | Dataset of allele and genotype frequencies of the three functionally significant polymorphisms of the MMP genes in Russian patients with primary open-angle glaucoma, essential hypertension and peptic ulcer |
title_short | Dataset of allele and genotype frequencies of the three functionally significant polymorphisms of the MMP genes in Russian patients with primary open-angle glaucoma, essential hypertension and peptic ulcer |
title_sort | dataset of allele and genotype frequencies of the three functionally significant polymorphisms of the mmp genes in russian patients with primary open angle glaucoma essential hypertension and peptic ulcer |
topic | Single nucleotide polymorphism Primary open-angle glaucoma Essential hypertension Peptic ulcer MMP |
url | http://www.sciencedirect.com/science/article/pii/S2352340920308982 |
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