Fetal, neonatal, and post-neonatal mortality in the 2015 Pelotas (Brazil) birth cohort and associated factors

This study aimed to describe fetal, neonatal, and post-neonatal mortality and associated factors in participants of the 2015 Pelotas (Brazil) birth cohort. The child mortality sub-study followed up all deaths in the first year of life. Data were collected on intrauterine fetal deaths (weight ≥ 500g...

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Main Authors: Andrea Ramirez Varela, Bruna Celestino Schneider, Susana Bubach, Mariangela Freitas Silveira, Andréa Dâmaso Bertoldi, Lina Sofia Moron Duarte, Ana Maria B. Menezes, Marlos R. Domingues, Diego G. Bassani
Format: Article
Language:English
Published: Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz
Series:Cadernos de Saúde Pública
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2019000905012&lng=en&tlng=en
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author Andrea Ramirez Varela
Bruna Celestino Schneider
Susana Bubach
Mariangela Freitas Silveira
Andréa Dâmaso Bertoldi
Lina Sofia Moron Duarte
Ana Maria B. Menezes
Marlos R. Domingues
Diego G. Bassani
author_facet Andrea Ramirez Varela
Bruna Celestino Schneider
Susana Bubach
Mariangela Freitas Silveira
Andréa Dâmaso Bertoldi
Lina Sofia Moron Duarte
Ana Maria B. Menezes
Marlos R. Domingues
Diego G. Bassani
author_sort Andrea Ramirez Varela
collection DOAJ
description This study aimed to describe fetal, neonatal, and post-neonatal mortality and associated factors in participants of the 2015 Pelotas (Brazil) birth cohort. The child mortality sub-study followed up all deaths in the first year of life. Data were collected on intrauterine fetal deaths (weight ≥ 500g and/or gestational age ≥ 20 weeks), neonatal deaths (< 28 days of life), and post-neonatal deaths (from 28 days to the end of the first year of life). Descriptive analyses using the Pearson chi-square test and a multinomial logistic regression to estimate the risk of fetal, neonatal, and post-neonatal deaths compared to live infants in the cohort (reference group) were performed. Data from 4,329 eligible births were collected, of which 54 died during the fetal period. Of the 4,275 eligible live births, 59 died in the first year of life. An association between fetal, neonatal, and post-neonatal deaths (OR = 15.60, 7.63, and 5.51 respectively) was found, as well as less than six prenatal consultations. Compared to live infants, fetal deaths were more likely to occur in non-white mothers, and neonatal deaths were 14.09 times more likely to occur in a preterm gestational age (< 37 weeks). Compared to live infants, infants that were born in a C-section delivery had 3.71 increased odds of post-neonatal death. Additionally, neonatal deaths were 102.37 times more likely to have a low Apgar score on the fifth minute after birth. These findings show the need for early interventions during pregnancy, ensuring access to adequate prenatal care.
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spelling doaj.art-ec3805a2fe5845739edb1cdd0c2222782022-12-21T19:20:26ZengEscola Nacional de Saúde Pública, Fundação Oswaldo CruzCadernos de Saúde Pública1678-446435710.1590/0102-311x00072918S0102-311X2019000905012Fetal, neonatal, and post-neonatal mortality in the 2015 Pelotas (Brazil) birth cohort and associated factorsAndrea Ramirez VarelaBruna Celestino SchneiderSusana BubachMariangela Freitas SilveiraAndréa Dâmaso BertoldiLina Sofia Moron DuarteAna Maria B. MenezesMarlos R. DominguesDiego G. BassaniThis study aimed to describe fetal, neonatal, and post-neonatal mortality and associated factors in participants of the 2015 Pelotas (Brazil) birth cohort. The child mortality sub-study followed up all deaths in the first year of life. Data were collected on intrauterine fetal deaths (weight ≥ 500g and/or gestational age ≥ 20 weeks), neonatal deaths (< 28 days of life), and post-neonatal deaths (from 28 days to the end of the first year of life). Descriptive analyses using the Pearson chi-square test and a multinomial logistic regression to estimate the risk of fetal, neonatal, and post-neonatal deaths compared to live infants in the cohort (reference group) were performed. Data from 4,329 eligible births were collected, of which 54 died during the fetal period. Of the 4,275 eligible live births, 59 died in the first year of life. An association between fetal, neonatal, and post-neonatal deaths (OR = 15.60, 7.63, and 5.51 respectively) was found, as well as less than six prenatal consultations. Compared to live infants, fetal deaths were more likely to occur in non-white mothers, and neonatal deaths were 14.09 times more likely to occur in a preterm gestational age (< 37 weeks). Compared to live infants, infants that were born in a C-section delivery had 3.71 increased odds of post-neonatal death. Additionally, neonatal deaths were 102.37 times more likely to have a low Apgar score on the fifth minute after birth. These findings show the need for early interventions during pregnancy, ensuring access to adequate prenatal care.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2019000905012&lng=en&tlng=enMortalidade InfantilEstudos de CoortesFatores de Risco
spellingShingle Andrea Ramirez Varela
Bruna Celestino Schneider
Susana Bubach
Mariangela Freitas Silveira
Andréa Dâmaso Bertoldi
Lina Sofia Moron Duarte
Ana Maria B. Menezes
Marlos R. Domingues
Diego G. Bassani
Fetal, neonatal, and post-neonatal mortality in the 2015 Pelotas (Brazil) birth cohort and associated factors
Cadernos de Saúde Pública
Mortalidade Infantil
Estudos de Coortes
Fatores de Risco
title Fetal, neonatal, and post-neonatal mortality in the 2015 Pelotas (Brazil) birth cohort and associated factors
title_full Fetal, neonatal, and post-neonatal mortality in the 2015 Pelotas (Brazil) birth cohort and associated factors
title_fullStr Fetal, neonatal, and post-neonatal mortality in the 2015 Pelotas (Brazil) birth cohort and associated factors
title_full_unstemmed Fetal, neonatal, and post-neonatal mortality in the 2015 Pelotas (Brazil) birth cohort and associated factors
title_short Fetal, neonatal, and post-neonatal mortality in the 2015 Pelotas (Brazil) birth cohort and associated factors
title_sort fetal neonatal and post neonatal mortality in the 2015 pelotas brazil birth cohort and associated factors
topic Mortalidade Infantil
Estudos de Coortes
Fatores de Risco
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2019000905012&lng=en&tlng=en
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