Identification of small diameter nerve fiber damage in hemodialysis patients' hands using the cutaneous silent period
Abstract Background The arteriovenous fistula is the most effective vascular access option for hemodialysis patients. An important and largely unreported concern detected at follow-up is the complaints of tingling or numbness in the hands of those patients. Furthermore, the cutaneous silent period q...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2023-08-01
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| Series: | The Egyptian Journal of Neurology, Psychiatry and Neurosurgery |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s41983-023-00704-9 |
| _version_ | 1797453511340851200 |
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| author | Ahmed Salama Al-Adl Hossam Abd El Monem Ali |
| author_facet | Ahmed Salama Al-Adl Hossam Abd El Monem Ali |
| author_sort | Ahmed Salama Al-Adl |
| collection | DOAJ |
| description | Abstract Background The arteriovenous fistula is the most effective vascular access option for hemodialysis patients. An important and largely unreported concern detected at follow-up is the complaints of tingling or numbness in the hands of those patients. Furthermore, the cutaneous silent period qualifies as a straightforward evaluation of small nerve fiber function. This study aims to evaluate the function of small-diameter nerve fibers in the hands of patients undergoing continuous hemodialysis (HD) on the side with the arteriovenous fistula (AVF) and on the contralateral side. Results A cross-sectional study of 40 randomly chosen patients with chronic kidney disease on regular hemodialysis three times weekly the cutaneous silent period (CSP) was recorded on the hand with and without AV fistula. The cutaneous silent period (CSP) CSP was elicited by electrical square pulse stimulation using standard bipolar electrodes. The average cutaneous silent period onset and end latencies demonstrated significant prolongation in the hemodialysis patient group (arteriovenous fistula and non-arteriovenous fistula) compared with the control group. Correlation between cutaneous silent period with hemodialysis duration and adequacy of hemodialysis (KT\V). There was a statistically negative correlation observed between cutaneous silent period onset latency on the arteriovenous side and a positive correlation with KT\V on non-arteriovenous fistula. side. Conclusions Hemodialysis patients recommended to undergo regular neurophysiological testing to check for small nerve fiber affection. In particular, measuring the cutaneous Silent period that provides a quick and noninvasive way to rule out small A-delta nerve malfunction. In addition, less nerve injury results from hemodialysis's increased efficiency. |
| first_indexed | 2024-03-09T15:23:54Z |
| format | Article |
| id | doaj.art-ec3ebcb15be4457698bb44e25b1aaf33 |
| institution | Directory Open Access Journal |
| issn | 1687-8329 |
| language | English |
| last_indexed | 2024-03-09T15:23:54Z |
| publishDate | 2023-08-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Neurology, Psychiatry and Neurosurgery |
| spelling | doaj.art-ec3ebcb15be4457698bb44e25b1aaf332023-11-26T12:39:31ZengSpringerOpenThe Egyptian Journal of Neurology, Psychiatry and Neurosurgery1687-83292023-08-015911610.1186/s41983-023-00704-9Identification of small diameter nerve fiber damage in hemodialysis patients' hands using the cutaneous silent periodAhmed Salama Al-Adl0Hossam Abd El Monem Ali1Internal Medicine Department, Damietta Faculty of Medicine, Al-Azhar UniversityNeurology Department, Damietta Faculty of Medicine, Al-Azhar UniversityAbstract Background The arteriovenous fistula is the most effective vascular access option for hemodialysis patients. An important and largely unreported concern detected at follow-up is the complaints of tingling or numbness in the hands of those patients. Furthermore, the cutaneous silent period qualifies as a straightforward evaluation of small nerve fiber function. This study aims to evaluate the function of small-diameter nerve fibers in the hands of patients undergoing continuous hemodialysis (HD) on the side with the arteriovenous fistula (AVF) and on the contralateral side. Results A cross-sectional study of 40 randomly chosen patients with chronic kidney disease on regular hemodialysis three times weekly the cutaneous silent period (CSP) was recorded on the hand with and without AV fistula. The cutaneous silent period (CSP) CSP was elicited by electrical square pulse stimulation using standard bipolar electrodes. The average cutaneous silent period onset and end latencies demonstrated significant prolongation in the hemodialysis patient group (arteriovenous fistula and non-arteriovenous fistula) compared with the control group. Correlation between cutaneous silent period with hemodialysis duration and adequacy of hemodialysis (KT\V). There was a statistically negative correlation observed between cutaneous silent period onset latency on the arteriovenous side and a positive correlation with KT\V on non-arteriovenous fistula. side. Conclusions Hemodialysis patients recommended to undergo regular neurophysiological testing to check for small nerve fiber affection. In particular, measuring the cutaneous Silent period that provides a quick and noninvasive way to rule out small A-delta nerve malfunction. In addition, less nerve injury results from hemodialysis's increased efficiency.https://doi.org/10.1186/s41983-023-00704-9Cutaneous silent periodArteriovenous fistulaHemodialysis |
| spellingShingle | Ahmed Salama Al-Adl Hossam Abd El Monem Ali Identification of small diameter nerve fiber damage in hemodialysis patients' hands using the cutaneous silent period The Egyptian Journal of Neurology, Psychiatry and Neurosurgery Cutaneous silent period Arteriovenous fistula Hemodialysis |
| title | Identification of small diameter nerve fiber damage in hemodialysis patients' hands using the cutaneous silent period |
| title_full | Identification of small diameter nerve fiber damage in hemodialysis patients' hands using the cutaneous silent period |
| title_fullStr | Identification of small diameter nerve fiber damage in hemodialysis patients' hands using the cutaneous silent period |
| title_full_unstemmed | Identification of small diameter nerve fiber damage in hemodialysis patients' hands using the cutaneous silent period |
| title_short | Identification of small diameter nerve fiber damage in hemodialysis patients' hands using the cutaneous silent period |
| title_sort | identification of small diameter nerve fiber damage in hemodialysis patients hands using the cutaneous silent period |
| topic | Cutaneous silent period Arteriovenous fistula Hemodialysis |
| url | https://doi.org/10.1186/s41983-023-00704-9 |
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