The Impact of Obesity on Nighttime Blood Pressure Dipping
<i>Background and objectives:</i> It is commonly known that obesity not only increases arterial hypertension (HT) risk but also impacts on the response to antihypertensives. This study aimed to assess blood pressure (BP) parameters based on Ambulatory Blood Pressure Measurement (ABPM) in...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-12-01
|
| Series: | Medicina |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1010-660X/56/12/700 |
| _version_ | 1797722237593190400 |
|---|---|
| author | Beata Moczulska Maciej Zechowicz Sylwia Leśniewska Karolina Osowiecka Leszek Gromadziński |
| author_facet | Beata Moczulska Maciej Zechowicz Sylwia Leśniewska Karolina Osowiecka Leszek Gromadziński |
| author_sort | Beata Moczulska |
| collection | DOAJ |
| description | <i>Background and objectives:</i> It is commonly known that obesity not only increases arterial hypertension (HT) risk but also impacts on the response to antihypertensives. This study aimed to assess blood pressure (BP) parameters based on Ambulatory Blood Pressure Measurement (ABPM) in obese patients. <i>Materials and Methods:</i> The study group consisted of 128 patients with obesity (BMI ≥ 30 kg/m<sup>2</sup>), with an average age of 43.25 years (±12.42), including 55 males and 73 females. They were divided into 2 groups: 1-with BMI ≥ 30 kg/m<sup>2</sup> and <40 kg/m<sup>2</sup>, 2-with BMI ≥ 40 kg/m<sup>2</sup>. Each patient underwent 24-h blood pressure monitoring. The average 24-h, daytime and nighttime systolic and diastolic pressure, as well as 24-h mean heart rate and % of nocturnal dip, were assessed. <i>Results:</i> Mean BMI in group 1 was 34.73 kg/m<sup>2</sup> (±2.96), and in group 2 it was 47.6 kg/m<sup>2</sup> (±6.3). Group 1 was significantly older than group 2 (46.5 vs. 39 years old). The analysis of ABPM revealed significantly higher BP values in all measurements in group 2 (i.e., systolic blood pressure (SBP) 24 h median = 132 mmHg; diastolic blood pressure (DBP) 24 h median = 84 mmHg). The nocturnal dip was greater in group 1 (8.95%). Mean 24-h heart rate was also higher in group 2 (median = 76 beats/min) than group 1 (median = 67.5 beats/min). More than half of patients in group 2 had been previously treated for HT, and based on ABPM, new HT was diagnosed in 6 patients from group 1 and 14 patients from group 2. Three groups of patients were identified based on nighttime dip: dipper, non-dipper, and reverse-dipper. No patient of the extreme dipper type was found. Group 2 comprised of significantly more patients of the reverse-dipper type. <i>Conclusions</i>: Patients with extreme morbid obesity frequently exhibit HT of the reverse-dipping pattern. This type is often linked with a higher risk of more advanced cardiovascular illness. |
| first_indexed | 2024-03-12T09:44:38Z |
| format | Article |
| id | doaj.art-ec418a5e35c048a886e83ee963cd8ea1 |
| institution | Directory Open Access Journal |
| issn | 1010-660X |
| language | English |
| last_indexed | 2024-03-12T09:44:38Z |
| publishDate | 2020-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-ec418a5e35c048a886e83ee963cd8ea12023-09-02T13:01:12ZengMDPI AGMedicina1010-660X2020-12-015670070010.3390/medicina56120700The Impact of Obesity on Nighttime Blood Pressure DippingBeata Moczulska0Maciej Zechowicz1Sylwia Leśniewska2Karolina Osowiecka3Leszek Gromadziński4II Clinic of Cardiology and Internal Medicine, Collegium Medicum, School of Medicine, University of Warmia and Mazury in Olsztyn, 11-041 Olsztyn, PolandII Clinic of Cardiology and Internal Medicine, Collegium Medicum, School of Medicine, University of Warmia and Mazury in Olsztyn, 11-041 Olsztyn, PolandII Clinic of Cardiology and Internal Medicine, Collegium Medicum, School of Medicine, University of Warmia and Mazury in Olsztyn, 11-041 Olsztyn, PolandDepartment of Public Health, Unit of Public Health, University of Warmia and Mazury in Olsztyn, 11-041 Olsztyn, PolandII Clinic of Cardiology and Internal Medicine, Collegium Medicum, School of Medicine, University of Warmia and Mazury in Olsztyn, 11-041 Olsztyn, Poland<i>Background and objectives:</i> It is commonly known that obesity not only increases arterial hypertension (HT) risk but also impacts on the response to antihypertensives. This study aimed to assess blood pressure (BP) parameters based on Ambulatory Blood Pressure Measurement (ABPM) in obese patients. <i>Materials and Methods:</i> The study group consisted of 128 patients with obesity (BMI ≥ 30 kg/m<sup>2</sup>), with an average age of 43.25 years (±12.42), including 55 males and 73 females. They were divided into 2 groups: 1-with BMI ≥ 30 kg/m<sup>2</sup> and <40 kg/m<sup>2</sup>, 2-with BMI ≥ 40 kg/m<sup>2</sup>. Each patient underwent 24-h blood pressure monitoring. The average 24-h, daytime and nighttime systolic and diastolic pressure, as well as 24-h mean heart rate and % of nocturnal dip, were assessed. <i>Results:</i> Mean BMI in group 1 was 34.73 kg/m<sup>2</sup> (±2.96), and in group 2 it was 47.6 kg/m<sup>2</sup> (±6.3). Group 1 was significantly older than group 2 (46.5 vs. 39 years old). The analysis of ABPM revealed significantly higher BP values in all measurements in group 2 (i.e., systolic blood pressure (SBP) 24 h median = 132 mmHg; diastolic blood pressure (DBP) 24 h median = 84 mmHg). The nocturnal dip was greater in group 1 (8.95%). Mean 24-h heart rate was also higher in group 2 (median = 76 beats/min) than group 1 (median = 67.5 beats/min). More than half of patients in group 2 had been previously treated for HT, and based on ABPM, new HT was diagnosed in 6 patients from group 1 and 14 patients from group 2. Three groups of patients were identified based on nighttime dip: dipper, non-dipper, and reverse-dipper. No patient of the extreme dipper type was found. Group 2 comprised of significantly more patients of the reverse-dipper type. <i>Conclusions</i>: Patients with extreme morbid obesity frequently exhibit HT of the reverse-dipping pattern. This type is often linked with a higher risk of more advanced cardiovascular illness.https://www.mdpi.com/1010-660X/56/12/700obesityABPMhypertension |
| spellingShingle | Beata Moczulska Maciej Zechowicz Sylwia Leśniewska Karolina Osowiecka Leszek Gromadziński The Impact of Obesity on Nighttime Blood Pressure Dipping Medicina obesity ABPM hypertension |
| title | The Impact of Obesity on Nighttime Blood Pressure Dipping |
| title_full | The Impact of Obesity on Nighttime Blood Pressure Dipping |
| title_fullStr | The Impact of Obesity on Nighttime Blood Pressure Dipping |
| title_full_unstemmed | The Impact of Obesity on Nighttime Blood Pressure Dipping |
| title_short | The Impact of Obesity on Nighttime Blood Pressure Dipping |
| title_sort | impact of obesity on nighttime blood pressure dipping |
| topic | obesity ABPM hypertension |
| url | https://www.mdpi.com/1010-660X/56/12/700 |
| work_keys_str_mv | AT beatamoczulska theimpactofobesityonnighttimebloodpressuredipping AT maciejzechowicz theimpactofobesityonnighttimebloodpressuredipping AT sylwialesniewska theimpactofobesityonnighttimebloodpressuredipping AT karolinaosowiecka theimpactofobesityonnighttimebloodpressuredipping AT leszekgromadzinski theimpactofobesityonnighttimebloodpressuredipping AT beatamoczulska impactofobesityonnighttimebloodpressuredipping AT maciejzechowicz impactofobesityonnighttimebloodpressuredipping AT sylwialesniewska impactofobesityonnighttimebloodpressuredipping AT karolinaosowiecka impactofobesityonnighttimebloodpressuredipping AT leszekgromadzinski impactofobesityonnighttimebloodpressuredipping |