A targeted proteomics screen reveals serum and synovial fluid proteomic signature in patients with gout

A targeted proteomics screen reveals serum and synovial fluid proteomic signature in patients with gout

ObjectiveTo characterize the inflammatory proteome in both serum and synovial fluid (SF) of patients with gout, in comparison to healthy controls and individuals with osteoarthritis (OA), by utilizing a high-quality, high-throughput proteomic analysis technique.MethodsUsing the Olink Target 48 Infla...

Podrobná bibliografie
Hlavní autoři:	Zhengping Huang, Xiaoyan Zhong, Yuexi Zhang, Xinjian Li, Meng Liu, Yukai Huang, Jian Yue, Guanqun Yi, Hongji Liu, Bingyan Yuan, Xu Chen, Shaoling Zheng, Tianwang Li
Médium:	Článek
Jazyk:	English
Vydáno:	Frontiers Media S.A. 2024-11-01
Edice:	Frontiers in Immunology
Témata:	crystal arthropathies osteoarthritis biomarkers synovial fluid analysis proteomics cytokines and inflammatory mediators
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1468810/full

Podobné jednotky

TMT-Based Quantitative Proteomics Analysis of Synovial Fluid-Derived Exosomes in Inflammatory Arthritis
Autor: Yukai Huang, a další
Vydáno: (2022-03-01)

Effects of ultrasound therapy on the synovial fluid proteome in a rabbit surgery-induced model of knee osteoarthritis
Autor: Qinglu Luo, a další
Vydáno: (2019-02-01)

Proteomic Analysis of Female Synovial Fluid to Identify Novel Biomarkers for Osteoarthritis
Autor: P. Robinson Muller, a další
Vydáno: (2023-02-01)

Case Report: Baricitinib as an Alternative in the Maintenance Therapy for Macrophage Activation Syndrome Secondary to Nodular Panniculitis
Autor: Guanqun Yi, a další
Vydáno: (2022-07-01)

The Usefulness of Synovial Fluid Proteome Analysis in Orthopaedics: Focus on Osteoarthritis and Periprosthetic Joint Infections
Autor: Davide Bizzoca, a další
Vydáno: (2022-10-01)

Proteome and phospholipidome interrelationship of synovial fluid-derived extracellular vesicles in equine osteoarthritis: An exploratory ‘multi-omics’ study to identify composite biomarkers
Autor: Emily Clarke, a další
Vydáno: (2024-03-01)

A significant difference of synovial mast cells in synovium from rotator cuff arthropathy compared to rotator cuff tears: A histological pilot study
Autor: Luca Farinelli, a další
Vydáno: (2024-09-01)

Implementation of telemedicine for knee osteoarthritis: study protocol for a randomized controlled trial
Autor: Zhengping Huang, a další
Vydáno: (2018-04-01)

Proteomic exploration of potential blood biomarkers in haemophilic arthropathy
Autor: Nataša Kalebota, a další
Vydáno: (2024-09-01)

Synovial chondromatosis affecting the temporomandibular joint: A case report and literature review
Autor: Ricardo J. Morales, a další
Vydáno: (2020-06-01)

MORPHOMETRIC ASPECTS OF STUDY OF FEATURES OF REMODELING OF MICROVESSELS OF SYNOVIAL MEMBRANE OF THE KNEE JOINT AT DIABETIC ARTHROPATHY
Autor: Hnatjuk M. S., a další
Vydáno: (2022-11-01)

Characterization of the porcine synovial fluid proteome and a comparison to the plasma proteome
Autor: Tue Bjerg Bennike, a další
Vydáno: (2015-12-01)

Giant Cell Tumor of Tendon Sheath and Tendinopathy as Early Features of Early Onset Sarcoidosis
Autor: Shaoling Zheng, a další
Vydáno: (2019-11-01)

Exosomes from the synovial microenvironment in joint homeostasis and osteoarthritis
Autor: Pooja N. Swami, a další
Vydáno: (2024-12-01)

Differences in the Synovial Fluid Proteome of Septic and Aseptic Implant Failure
Autor: Andrea Sowislok, a další
Vydáno: (2024-04-01)

Synovial fluid proteome profile of surgical versus chemical induced osteoarthritis in rabbits
Autor: Sharifah Zakiah Syed Sulaiman, a další
Vydáno: (2022-02-01)

Changes in synovial fluid biomarkers after experimental equine osteoarthritis
Autor: Ma Tian-wen, a další
Vydáno: (2017-12-01)

FAMILIAL CAMPTODACTYLY COXA VARA PERICARDITIS SYNDROME MASQUARADING AS JUVUNILE IDIOPATHIC ARTHRITIS
Autor: Shahzadi Sumbal Ghazi, a další
Vydáno: (2018-12-01)

Effects of synovial macrophages in osteoarthritis
Autor: Kun Zhao, a další
Vydáno: (2023-07-01)

Impact of Isolation Procedures on the Development of a Preclinical Synovial Fibroblasts/Macrophages in an In Vitro Model of Osteoarthritis
Autor: Cristina Manferdini, a další
Vydáno: (2020-12-01)

Bibliometric analysis of synovial in osteoarthritis in the last 10 years
Autor: Guangtao Han, a další
Vydáno: (2024-07-01)

Extraction and identification of synovial tissue-derived exosomes by different separation techniques
Autor: Pu Chen, a další
Vydáno: (2020-03-01)

Characterization of the inflammatory proteome of synovial fluid from patients with psoriatic arthritis: Potential treatment targets
Autor: Nuria Barbarroja, a další
Vydáno: (2023-03-01)

Two independent proteomic approaches provide a comprehensive analysis of the synovial fluid proteome response to Autologous Chondrocyte Implantation
Autor: Charlotte H. Hulme, a další
Vydáno: (2018-05-01)

RNAseq of Osteoarthritic Synovial Tissues: Systematic Literary Review
Autor: Logan Moore, a další
Vydáno: (2022-05-01)

Profiling of inflammatory mediators in the synovial fluid related to pain in knee osteoarthritis
Autor: Li Li, a další
Vydáno: (2020-02-01)

Identification of key biomarkers and immune infiltration in the synovial tissue of osteoarthritis by bioinformatics analysis
Autor: Weisong Cai, a další
Vydáno: (2020-01-01)

Curcumin Inhibits Proliferation of Synovial Cells by Downregulating Expression of Matrix Metalloproteinase‐3 in Osteoarthritis
Autor: Jian‐jun Zeng, a další
Vydáno: (2019-02-01)

Management of temporomandibular joint diseases: a rare case report of coexisting calcium pyrophosphate crystal deposition and synovial chondromatosis
Autor: Makoto Murahashi, a další
Vydáno: (2022-12-01)

Application for proteomic techniques in studying osteoarthritis: a review
Autor: Myriam eGharbi, a další
Vydáno: (2011-12-01)

The potential role of synovial cells in the progression and treatment of osteoarthritis
Autor: Zaijun Zou, a další
Vydáno: (2023-10-01)

Exploring the Psoriatic Arthritis Proteome in Search of Novel Biomarkers
Autor: Shalini M. Mahendran, a další
Vydáno: (2018-01-01)

Mechanical Stress Induces Sodium Entry and Osmoprotective Responses in Murine Synovial Fibroblasts
Autor: Annemarie Proff, a další
Vydáno: (2024-03-01)

Synovial Chondromatosis in Woman with Symptoms Mimicking Early Stages Osteoarthritis: Case Report
Autor: Bagus Wibowo Soetojo, a další
Vydáno: (2020-01-01)

Single-cell profiling uncovers synovial fibroblast subpopulations associated with chondrocyte injury in osteoarthritis
Autor: Zezhong Liu, a další
Vydáno: (2024-12-01)

Friction of osteoarthritic cartilage with patient-specific synovial fluid: Effect of different loading conditions
Autor: Luisa de Roy, a další
Vydáno: (2025-03-01)

Gout mimicking spondyloarthritis: case report and literature review
Autor: Chen W, a další
Vydáno: (2017-06-01)

Association of Cartilage, Synovial Fluid and Membrane Pathological Findings in Serbian Mountain Horses Without Signs of Lameness
Autor: Marković Lazar, a další
Vydáno: (2024-09-01)

Diagnostic Accuracy of Ultrasound in Detection of Synovial Hypertrophy in Patients with Osteoarthritis
Autor: Sidra Manzoor
Vydáno: (2017-12-01)

Association of synovial expression of growth and differentiation factor 5 (GDF5) with radiographic severity of knee osteoarthritis
Autor: Bhee Witoonpanich, a další
Vydáno: (2022-11-01)