Mania with malignant catatonia due to nonpara neoplastic Anti-N-methyl-D-aspartate-Receptor encephalitis in a 29-year-old female – A rare entity
Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is a rare neurological autoimmune encephalitis. Its symptoms may mimic psychosis as this disease is neurological disorder in psychiatric costume. Disparity in clinical symptoms and nonsupportive laboratory investigations except the cerebrospinal...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | Journal of the Scientific Society |
| Subjects: | |
| Online Access: | http://www.jscisociety.com/article.asp?issn=0974-5009;year=2021;volume=48;issue=1;spage=41;epage=45;aulast=Garg |
| _version_ | 1818915355994619904 |
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| author | Sunny Garg Alka Chauhan |
| author_facet | Sunny Garg Alka Chauhan |
| author_sort | Sunny Garg |
| collection | DOAJ |
| description | Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is a rare neurological autoimmune encephalitis. Its symptoms may mimic psychosis as this disease is neurological disorder in psychiatric costume. Disparity in clinical symptoms and nonsupportive laboratory investigations except the cerebrospinal fluid (CSF) analysis delays the diagnosis. We presented a case of 29-year-old female with psychiatric symptoms such as suspiciousness, decreased sleep, and boastfulness. Within few days, the patient developed neurological symptoms like seizures, disorientation, while the patient was on antipsychotic and benzodiazepines. Her symptoms worsened and the patient entered into the catatonic phase of the illness along with autonomic instability. We reached a positive diagnosis of Anti-NMDA encephalitis through CSF analysis. The patient recovered completely with the help of immunotherapy and intensive cognitive rehabilitation. This case emphasizes the need of a multidisciplinary approach in the management, early detection, and adequate treatment of this challenging illness for the better outcome of the patient. |
| first_indexed | 2024-12-20T00:00:58Z |
| format | Article |
| id | doaj.art-ec48c318e1984f9cb916a19d8370991c |
| institution | Directory Open Access Journal |
| issn | 0974-5009 |
| language | English |
| last_indexed | 2024-12-20T00:00:58Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of the Scientific Society |
| spelling | doaj.art-ec48c318e1984f9cb916a19d8370991c2022-12-21T20:00:50ZengWolters Kluwer Medknow PublicationsJournal of the Scientific Society0974-50092021-01-01481414510.4103/jss.jss_107_20Mania with malignant catatonia due to nonpara neoplastic Anti-N-methyl-D-aspartate-Receptor encephalitis in a 29-year-old female – A rare entitySunny GargAlka ChauhanAnti-N-methyl-D-aspartate (NMDA) receptor encephalitis is a rare neurological autoimmune encephalitis. Its symptoms may mimic psychosis as this disease is neurological disorder in psychiatric costume. Disparity in clinical symptoms and nonsupportive laboratory investigations except the cerebrospinal fluid (CSF) analysis delays the diagnosis. We presented a case of 29-year-old female with psychiatric symptoms such as suspiciousness, decreased sleep, and boastfulness. Within few days, the patient developed neurological symptoms like seizures, disorientation, while the patient was on antipsychotic and benzodiazepines. Her symptoms worsened and the patient entered into the catatonic phase of the illness along with autonomic instability. We reached a positive diagnosis of Anti-NMDA encephalitis through CSF analysis. The patient recovered completely with the help of immunotherapy and intensive cognitive rehabilitation. This case emphasizes the need of a multidisciplinary approach in the management, early detection, and adequate treatment of this challenging illness for the better outcome of the patient.http://www.jscisociety.com/article.asp?issn=0974-5009;year=2021;volume=48;issue=1;spage=41;epage=45;aulast=Garganti-n-methyl-d-aspartate encephalitiscerebrospinal fluid analysisimmunotherapymalignant catatonianeuropsychiatric |
| spellingShingle | Sunny Garg Alka Chauhan Mania with malignant catatonia due to nonpara neoplastic Anti-N-methyl-D-aspartate-Receptor encephalitis in a 29-year-old female – A rare entity Journal of the Scientific Society anti-n-methyl-d-aspartate encephalitis cerebrospinal fluid analysis immunotherapy malignant catatonia neuropsychiatric |
| title | Mania with malignant catatonia due to nonpara neoplastic Anti-N-methyl-D-aspartate-Receptor encephalitis in a 29-year-old female – A rare entity |
| title_full | Mania with malignant catatonia due to nonpara neoplastic Anti-N-methyl-D-aspartate-Receptor encephalitis in a 29-year-old female – A rare entity |
| title_fullStr | Mania with malignant catatonia due to nonpara neoplastic Anti-N-methyl-D-aspartate-Receptor encephalitis in a 29-year-old female – A rare entity |
| title_full_unstemmed | Mania with malignant catatonia due to nonpara neoplastic Anti-N-methyl-D-aspartate-Receptor encephalitis in a 29-year-old female – A rare entity |
| title_short | Mania with malignant catatonia due to nonpara neoplastic Anti-N-methyl-D-aspartate-Receptor encephalitis in a 29-year-old female – A rare entity |
| title_sort | mania with malignant catatonia due to nonpara neoplastic anti n methyl d aspartate receptor encephalitis in a 29 year old female a rare entity |
| topic | anti-n-methyl-d-aspartate encephalitis cerebrospinal fluid analysis immunotherapy malignant catatonia neuropsychiatric |
| url | http://www.jscisociety.com/article.asp?issn=0974-5009;year=2021;volume=48;issue=1;spage=41;epage=45;aulast=Garg |
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