Effect of COVID-19 on childhood Mycoplasma pneumoniae infection in Chengdu, China
Abstract Background Following the outbreak of the COVID-19 pandemic, a change in the incidence and transmission of respiratory pathogens was observed. Here, we retrospectively analyzed the impact of COVID-19 on the epidemiologic characteristics of Mycoplasma pneumoniae infection among children in Ch...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2021-04-01
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| Series: | BMC Pediatrics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12887-021-02679-z |
| _version_ | 1819023492555735040 |
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| author | Ying Zhang Yijie Huang Tao Ai Jun Luo Hanmin Liu |
| author_facet | Ying Zhang Yijie Huang Tao Ai Jun Luo Hanmin Liu |
| author_sort | Ying Zhang |
| collection | DOAJ |
| description | Abstract Background Following the outbreak of the COVID-19 pandemic, a change in the incidence and transmission of respiratory pathogens was observed. Here, we retrospectively analyzed the impact of COVID-19 on the epidemiologic characteristics of Mycoplasma pneumoniae infection among children in Chengdu, one of the largest cities of western China. Method M. pneumoniae infection was diagnosed in 33,345 pediatric patients with respiratory symptoms at the Chengdu Women’s & Children’s Central Hospital between January 2017 and December 2020, based on a serum antibody titer of ≥1:160 measured by the passive agglutination assay. Differences in infection rates were examined by sex, age, and temporal distribution. Results Two epidemic outbreaks occurred between October-December 2017 and April-December 2019, and two infection peaks were detected in the second and fourth quarters of 2017, 2018, and 2019. Due to the public health response to COVID-19, the number of positive M. pneumoniae cases significantly decreased in the second quarter of 2020. The number of M. pneumoniae infection among children aged 3–6 years was higher than that in other age groups. Conclusions Preschool children are more susceptible to M. pneumoniae infection and close contact appears to be the predominant factor favoring pathogen transmission. The public health response to COVID-19 can effectively control the transmission of M. pneumoniae. |
| first_indexed | 2024-12-21T04:39:45Z |
| format | Article |
| id | doaj.art-ec49eb894a3441dcb23016a430f8ad87 |
| institution | Directory Open Access Journal |
| issn | 1471-2431 |
| language | English |
| last_indexed | 2024-12-21T04:39:45Z |
| publishDate | 2021-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pediatrics |
| spelling | doaj.art-ec49eb894a3441dcb23016a430f8ad872022-12-21T19:15:45ZengBMCBMC Pediatrics1471-24312021-04-012111610.1186/s12887-021-02679-zEffect of COVID-19 on childhood Mycoplasma pneumoniae infection in Chengdu, ChinaYing Zhang0Yijie Huang1Tao Ai2Jun Luo3Hanmin Liu4Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), West China Second University Hospital, Ministry of Education, Sichuan UniversityChildren respiratory department,Chengdu Women’s and Children’s Central Hospital, School of Medicine, University of Electronic Science and Technology of ChinaChildren respiratory department,Chengdu Women’s and Children’s Central Hospital, School of Medicine, University of Electronic Science and Technology of ChinaChildren respiratory department,Chengdu Women’s and Children’s Central Hospital, School of Medicine, University of Electronic Science and Technology of ChinaKey Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), West China Second University Hospital, Ministry of Education, Sichuan UniversityAbstract Background Following the outbreak of the COVID-19 pandemic, a change in the incidence and transmission of respiratory pathogens was observed. Here, we retrospectively analyzed the impact of COVID-19 on the epidemiologic characteristics of Mycoplasma pneumoniae infection among children in Chengdu, one of the largest cities of western China. Method M. pneumoniae infection was diagnosed in 33,345 pediatric patients with respiratory symptoms at the Chengdu Women’s & Children’s Central Hospital between January 2017 and December 2020, based on a serum antibody titer of ≥1:160 measured by the passive agglutination assay. Differences in infection rates were examined by sex, age, and temporal distribution. Results Two epidemic outbreaks occurred between October-December 2017 and April-December 2019, and two infection peaks were detected in the second and fourth quarters of 2017, 2018, and 2019. Due to the public health response to COVID-19, the number of positive M. pneumoniae cases significantly decreased in the second quarter of 2020. The number of M. pneumoniae infection among children aged 3–6 years was higher than that in other age groups. Conclusions Preschool children are more susceptible to M. pneumoniae infection and close contact appears to be the predominant factor favoring pathogen transmission. The public health response to COVID-19 can effectively control the transmission of M. pneumoniae.https://doi.org/10.1186/s12887-021-02679-zMycoplasma pneumoniaeCOVID-19 pandemicChildrenWestern China |
| spellingShingle | Ying Zhang Yijie Huang Tao Ai Jun Luo Hanmin Liu Effect of COVID-19 on childhood Mycoplasma pneumoniae infection in Chengdu, China BMC Pediatrics Mycoplasma pneumoniae COVID-19 pandemic Children Western China |
| title | Effect of COVID-19 on childhood Mycoplasma pneumoniae infection in Chengdu, China |
| title_full | Effect of COVID-19 on childhood Mycoplasma pneumoniae infection in Chengdu, China |
| title_fullStr | Effect of COVID-19 on childhood Mycoplasma pneumoniae infection in Chengdu, China |
| title_full_unstemmed | Effect of COVID-19 on childhood Mycoplasma pneumoniae infection in Chengdu, China |
| title_short | Effect of COVID-19 on childhood Mycoplasma pneumoniae infection in Chengdu, China |
| title_sort | effect of covid 19 on childhood mycoplasma pneumoniae infection in chengdu china |
| topic | Mycoplasma pneumoniae COVID-19 pandemic Children Western China |
| url | https://doi.org/10.1186/s12887-021-02679-z |
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