Endoplasmic reticulum stress impairs insulin receptor signaling in the brains of obese rats.
The incidence of obesity is increasing worldwide. It was reported that endoplasmic reticulum stress (ERS) could inhibit insulin receptor signaling by activating c-Jun N-terminal kinase (JNK) in the liver. However, the relationship between ERS and insulin receptor signaling in the brain during obesit...
| Autors principals: | , , , , , , , , |
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| Format: | Article |
| Idioma: | English |
| Publicat: |
Public Library of Science (PLoS)
2015-01-01
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| Col·lecció: | PLoS ONE |
| Accés en línia: | http://europepmc.org/articles/PMC4433117?pdf=render |