MECHANICAL FORCES ACCELERATE COLLAGEN DIGESTION BY BACTERIAL COLLAGENASE IN LUNG TISSUE STRIPS

MECHANICAL FORCES ACCELERATE COLLAGEN DIGESTION BY BACTERIAL COLLAGENASE IN LUNG TISSUE STRIPS

Most tissues in the body are under mechanical tension, and while enzymes mediate many cellular and extracellular processes, the effects of mechanical forces on enzyme reactions in the native extracellular matrix (ECM) are not fully understood. We hypothesized that physiological levels of mechanical...

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Bibliographic Details
Main Authors: Eunice Yi, Susumu Sato, Ayuko Takahashi, Harikrishnan Parameswaran, Todd A Blute, Erzsébet Bartolák-Suki, Bela Suki
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-07-01
Series:Frontiers in Physiology
Subjects:
Microscopy, Electron
computational model
stretch
stiffness
Cleavage
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00287/full

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