Activation of skeletal muscle–resident glial cells upon nerve injury

Activation of skeletal muscle–resident glial cells upon nerve injury

Here, we report on the identification of Itga7-expressing muscle-resident glial cells activated by loss of neuromuscular junction (NMJ) integrity. Gene expression analysis at the bulk and single-cell level revealed that these cells are distinct from Itga7-expressing muscle satellite cells. We show t...

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Bibliographic Details
Main Authors: Daisy Proietti, Lorenzo Giordani, Marco De Bardi, Chiara D’Ercole, Biliana Lozanoska-Ochser, Susanna Amadio, Cinzia Volonté, Sara Marinelli, Antoine Muchir, Marina Bouché, Giovanna Borsellino, Alessandra Sacco, Pier Lorenzo Puri, Luca Madaro
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-04-01
Series:JCI Insight
Subjects:
Muscle biology
Online Access:https://doi.org/10.1172/jci.insight.143469

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