A bioluminescent imaging mouse model for Marburg virus based on a pseudovirus system

A bioluminescent imaging mouse model for Marburg virus based on a pseudovirus system

Marburg virus (MARV) can cause lethal hemorrhagic fever in humans. Handling of MARV is restricted to high-containment biosafety level 4 (BSL-4) facilities, which greatly impedes research into this virus. In this study, a high titer of MARV pseudovirus was generated through optimization of the HIV ba...

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Bibliographic Details
Main Authors: Li Zhang, Qianqian Li, Qiang Liu, Weijin Huang, Jianhui Nie, Youchun Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2017-08-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
animal model
bioluminescent imaging
marburg virus
passive protection
pseudovirus
Online Access:http://dx.doi.org/10.1080/21645515.2017.1325050

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