Correction of Stress Hyperglycemia in Patients with Acute Surgical Abdominal Diseases

Critically ill patients admitted to intensive care units for the clinical manifestations of stress hyperglycemia represent a group in which attempts are most frequently undertaken to employ various methods of its correction. Objective: to compare different techniques for correction of stress hypergl...

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Main Authors: A. V. Nikolenko, I. N. Prelous, I. N. Leiderman
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2013-04-01
Series:Общая реаниматология
Subjects:
Online Access:https://www.reanimatology.com/rmt/article/view/145
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author A. V. Nikolenko
I. N. Prelous
I. N. Leiderman
author_facet A. V. Nikolenko
I. N. Prelous
I. N. Leiderman
author_sort A. V. Nikolenko
collection DOAJ
description Critically ill patients admitted to intensive care units for the clinical manifestations of stress hyperglycemia represent a group in which attempts are most frequently undertaken to employ various methods of its correction. Objective: to compare different techniques for correction of stress hyperglycemia in patients with acute surgical abdominal disease complicated by peritonitis. Materials and methods: In this single-center randomized controlled trial, stress hyperglycemia was corrected by different procedures in 60 patients with acute surgical abdominal disease complicated by peritonitis. Results: As compared with traditional procedures for correction of stress hyperglycemia, the human insulin analogue aspart (Novorapid) improves stressful glycemic control and reduces the risk of hypoglycemia. During intensive insulin therapy, the ultrashort-acting insulin group showed showed a trend for a reduction in the number of manifestations of multiple organ failure and signs of systemic inflammation and decline in the number of hospital days. The least duration of mechanical ventilation was noted in the small-volume food group.
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spelling doaj.art-ec5805a1f30341c59f452a020b606d932023-03-13T09:32:52ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102013-04-019210.15360/1813-9779-2013-2-29145Correction of Stress Hyperglycemia in Patients with Acute Surgical Abdominal DiseasesA. V. NikolenkoI. N. PrelousI. N. LeidermanCritically ill patients admitted to intensive care units for the clinical manifestations of stress hyperglycemia represent a group in which attempts are most frequently undertaken to employ various methods of its correction. Objective: to compare different techniques for correction of stress hyperglycemia in patients with acute surgical abdominal disease complicated by peritonitis. Materials and methods: In this single-center randomized controlled trial, stress hyperglycemia was corrected by different procedures in 60 patients with acute surgical abdominal disease complicated by peritonitis. Results: As compared with traditional procedures for correction of stress hyperglycemia, the human insulin analogue aspart (Novorapid) improves stressful glycemic control and reduces the risk of hypoglycemia. During intensive insulin therapy, the ultrashort-acting insulin group showed showed a trend for a reduction in the number of manifestations of multiple organ failure and signs of systemic inflammation and decline in the number of hospital days. The least duration of mechanical ventilation was noted in the small-volume food group.https://www.reanimatology.com/rmt/article/view/145stress hyperglycemiacritical conditionsintensive insulin therapy.
spellingShingle A. V. Nikolenko
I. N. Prelous
I. N. Leiderman
Correction of Stress Hyperglycemia in Patients with Acute Surgical Abdominal Diseases
Общая реаниматология
stress hyperglycemia
critical conditions
intensive insulin therapy.
title Correction of Stress Hyperglycemia in Patients with Acute Surgical Abdominal Diseases
title_full Correction of Stress Hyperglycemia in Patients with Acute Surgical Abdominal Diseases
title_fullStr Correction of Stress Hyperglycemia in Patients with Acute Surgical Abdominal Diseases
title_full_unstemmed Correction of Stress Hyperglycemia in Patients with Acute Surgical Abdominal Diseases
title_short Correction of Stress Hyperglycemia in Patients with Acute Surgical Abdominal Diseases
title_sort correction of stress hyperglycemia in patients with acute surgical abdominal diseases
topic stress hyperglycemia
critical conditions
intensive insulin therapy.
url https://www.reanimatology.com/rmt/article/view/145
work_keys_str_mv AT avnikolenko correctionofstresshyperglycemiainpatientswithacutesurgicalabdominaldiseases
AT inprelous correctionofstresshyperglycemiainpatientswithacutesurgicalabdominaldiseases
AT inleiderman correctionofstresshyperglycemiainpatientswithacutesurgicalabdominaldiseases