Testosterone replacement and prostate cancer
This article is intended as a review of the available clinical data outlining the risks and benefits of testosterone (androgen) replacement therapy, specifically addressing the issue of the relationship between exogenous androgen administration and prostate cancer risk. There is controversy over whe...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2012-01-01
|
| Series: | Indian Journal of Urology |
| Subjects: | |
| Online Access: | http://www.indianjurol.com/article.asp?issn=0970-1591;year=2012;volume=28;issue=2;spage=123;epage=128;aulast=Ramasamy |
| _version_ | 1798043399470710784 |
|---|---|
| author | Ranjith Ramasamy Erik S Fisher Peter N Schlegel |
| author_facet | Ranjith Ramasamy Erik S Fisher Peter N Schlegel |
| author_sort | Ranjith Ramasamy |
| collection | DOAJ |
| description | This article is intended as a review of the available clinical data outlining the risks and benefits of testosterone (androgen) replacement therapy, specifically addressing the issue of the relationship between exogenous androgen administration and prostate cancer risk. There is controversy over whether androgen replacement is a risk factor for incident prostate cancer. Our review of current clinical information revealed that to date, no study or review has definitively shown that androgen replacement therapy is an independent risk factor for development of prostate cancer. Androgen administration seems to be beneficial in decreasing fatal cardiovascular events, body fat mass, and insulin resistance. Overall, the current clinical data seems to suggest that androgen replacement is an appropriate therapeutic option for men with symptomatic hypogonadism provided that patients continue to receive regular prostate screenings. |
| first_indexed | 2024-04-11T22:48:32Z |
| format | Article |
| id | doaj.art-ec58de5f411f4b7ea7e4acaa413ec076 |
| institution | Directory Open Access Journal |
| issn | 0970-1591 1998-3824 |
| language | English |
| last_indexed | 2024-04-11T22:48:32Z |
| publishDate | 2012-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Urology |
| spelling | doaj.art-ec58de5f411f4b7ea7e4acaa413ec0762022-12-22T03:58:41ZengWolters Kluwer Medknow PublicationsIndian Journal of Urology0970-15911998-38242012-01-0128212312810.4103/0970-1591.98449Testosterone replacement and prostate cancerRanjith RamasamyErik S FisherPeter N SchlegelThis article is intended as a review of the available clinical data outlining the risks and benefits of testosterone (androgen) replacement therapy, specifically addressing the issue of the relationship between exogenous androgen administration and prostate cancer risk. There is controversy over whether androgen replacement is a risk factor for incident prostate cancer. Our review of current clinical information revealed that to date, no study or review has definitively shown that androgen replacement therapy is an independent risk factor for development of prostate cancer. Androgen administration seems to be beneficial in decreasing fatal cardiovascular events, body fat mass, and insulin resistance. Overall, the current clinical data seems to suggest that androgen replacement is an appropriate therapeutic option for men with symptomatic hypogonadism provided that patients continue to receive regular prostate screenings.http://www.indianjurol.com/article.asp?issn=0970-1591;year=2012;volume=28;issue=2;spage=123;epage=128;aulast=RamasamyAndrogen replacementhypogonadismprostate |
| spellingShingle | Ranjith Ramasamy Erik S Fisher Peter N Schlegel Testosterone replacement and prostate cancer Indian Journal of Urology Androgen replacement hypogonadism prostate |
| title | Testosterone replacement and prostate cancer |
| title_full | Testosterone replacement and prostate cancer |
| title_fullStr | Testosterone replacement and prostate cancer |
| title_full_unstemmed | Testosterone replacement and prostate cancer |
| title_short | Testosterone replacement and prostate cancer |
| title_sort | testosterone replacement and prostate cancer |
| topic | Androgen replacement hypogonadism prostate |
| url | http://www.indianjurol.com/article.asp?issn=0970-1591;year=2012;volume=28;issue=2;spage=123;epage=128;aulast=Ramasamy |
| work_keys_str_mv | AT ranjithramasamy testosteronereplacementandprostatecancer AT eriksfisher testosteronereplacementandprostatecancer AT peternschlegel testosteronereplacementandprostatecancer |