Comparative Evaluation of the Activity of Various Lentiviral Vectors Containing Three Anti-HIV Genes

Comparative Evaluation of the Activity of Various Lentiviral Vectors Containing Three Anti-HIV Genes

A promising direction in the treatment of HIV infection is a gene therapy approach based on the insertion of antiviral genes aimed at inhibiting HIV replication into the genome of host cells. We obtained six constructs of lentiviral vectors with different arrangements of three antiviral genes: micro...

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Bibliographic Details
Main Authors: Olga Vladimirovna Orlova, Dina Viktorovna Glazkova, Ramil Rafailovich Mintaev, Galina Mikhailovna Tsyganova, Felix Anatolevich Urusov, German Alexandrovich Shipulin, Elena Vladimirovna Bogoslovskaya
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Microorganisms
Subjects:
lentiviral vectors
TRIM5a
human immunodeficiency virus type 1 (HIV-1)
C-peptide
miRNA
Online Access:https://www.mdpi.com/2076-2607/11/4/1053

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https://www.mdpi.com/2076-2607/11/4/1053

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