RAGE and HMGB1 Expression in Orbital Tissue Microenvironment in Graves’ Ophthalmopathy
Graves’ ophthalmopathy (GO) is a chronic autoimmune inflammatory disorder involving orbital tissues. A receptor for advanced glycation end products (RAGE) and its ligand high mobility group box 1 (HMGB1) protein trigger inflammation and cell proliferation and are involved in the pathogenesis of vari...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2021-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2021/8891324 |