Allele summation of diabetes risk genes predicts impaired glucose tolerance in female and obese individuals.

Allele summation of diabetes risk genes predicts impaired glucose tolerance in female and obese individuals.

INTRODUCTION: Single nucleotide polymorphisms (SNPs) in approximately 40 genes have been associated with an increased risk for type 2 diabetes (T2D) in genome-wide association studies. It is not known whether a similar genetic impact on the risk of prediabetes (impaired glucose tolerance [IGT] or im...

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Main Authors: Katarzyna Linder, Robert Wagner, Erifili Hatziagelaki, Caroline Ketterer, Martin Heni, Fausto Machicao, Norbert Stefan, Harald Staiger, Hans-Ulrich Häring, Andreas Fritsche
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3387191?pdf=render

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