Saint John's wort, an herbal inducer of the cytochrome P4503A4 isoform, may alleviate symptoms of Willis-Ekbom's disease

Saint John's wort, an herbal inducer of the cytochrome P4503A4 isoform, may alleviate symptoms of Willis-Ekbom's disease

OBJECTIVE: Certain drug classes alleviate the symptoms of Willis-Ekbom's disease, whereas others aggravate them. The pharmacological profiles of these drugs suggest that drugs that alleviate Willis-Ekbom's disease inhibit thyroid hormone activity, whereas drugs that aggravate Willis-Ekbom&...

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Bibliographic Details
Main Authors:	José Carlos Pereira Jr, Márcia Pradella-Hallinan, Rosana Cardoso Alves
Format:	Article
Language:	English
Published:	Elsevier España 2013-04-01
Series:	Clinics
Subjects:	Willis-Ekbom's Disease Restless Legs Syndrome Treatment Restless Legs Syndrome Saint John's Wort Thyroid Hormone CYP4503A4
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322013000400469

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