SNP-by-CpG Site Interactions in <i>ABCA7</i> Are Associated with Cognition in Older African Americans
SNPs in <i>ABCA7</i> confer the largest genetic risk for Alzheimer’s Disease (AD) in African Americans (AA) after <i>APOE</i> ε4. However, the relationship between <i>ABCA7</i> and cognitive function has not been thoroughly examined. We investigated the effects of...
Main Authors: | Dima L. Chaar, Kim Nguyen, Yi-Zhe Wang, Scott M. Ratliff, Thomas H. Mosley, Sharon L. R. Kardia, Jennifer A. Smith, Wei Zhao |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-11-01
|
Series: | Genes |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4425/13/11/2150 |
Similar Items
-
The Effects of APOE and ABCA7 on Cognitive Function and Alzheimer’s Disease Risk in African Americans: A Focused Mini Review
by: Chelsie N. Berg, et al.
Published: (2019-11-01) -
An Overview of the Genetics of <i>ABCA4</i> Retinopathies, an Evolving Story
by: Saoud Al-Khuzaei, et al.
Published: (2021-08-01) -
Molecular Analysis of the <i>ABCA4</i> Gene Mutations in Patients with Stargardt Disease Using Human Hair Follicles
by: Aneta Ścieżyńska, et al.
Published: (2020-05-01) -
Erythrokeratodermia Variabilis-like Phenotype in Patients Carrying <i>ABCA12</i> Mutations
by: Alrun Hotz, et al.
Published: (2024-02-01) -
Examining the efficacy of a cardio-dance intervention on brain health and the moderating role of ABCA7 in older African Americans: a protocol for a randomized controlled trial
by: Mark A. Gluck, et al.
Published: (2023-11-01)