Phyllodes tumor of the breast: diagnosis, management and outcome during a 10-year experience
Chagkrit Ditsatham,1 Wilaiwan Chongruksut21Division of Head, Neck, and Breast Surgery, Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; 2Research Unit, Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, ThailandCorrespondence: Chagk...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2019-08-01
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| Series: | Cancer Management and Research |
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| Online Access: | https://www.dovepress.com/phyllodes-tumor-of-the-breast-diagnosis-management-and-outcome-during--peer-reviewed-article-CMAR |
| _version_ | 1828351425956020224 |
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| author | Ditsatham C Chongruksut W |
| author_facet | Ditsatham C Chongruksut W |
| author_sort | Ditsatham C |
| collection | DOAJ |
| description | Chagkrit Ditsatham,1 Wilaiwan Chongruksut21Division of Head, Neck, and Breast Surgery, Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; 2Research Unit, Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, ThailandCorrespondence: Chagkrit DitsathamDepartment of Surgery, Faculty of Medicine, Chiang Mai University, 110 Intavaroros Road, Amphoe Muang, Chiang Mai 50200, ThailandTel +66 5 394 5532Fax +66 5 394 6139Email nansurg7@gmail.comBackground: Phyllodes tumor is a very rare tumor of the breast, incidence being 0.3–0.9% of all breast tumors. Phyllodes tumors are classified into three grades: benign, borderline or malignant. The aim of this study was to investigate patient characteristics, imaging characteristic findings, surgical treatment and outcome of phyllodes tumor.Materials and methods: This is a retrospective review of phyllodes tumor patients who had undergone surgical management between 1 January 2006 and 31 December 2015 in Head, Neck and Breast Unit, Department of Surgery, Chiang Mai University Hospital.Results: A total of 188 phyllodes tumor patients were included in this study. The average age of the patients was 35.6 years. The majority of the tumors were of lobulated shape. Tumor morphology from imaging: lobulated shaped tumor 112 cases, oval-shape 37 cases, round shape 8 cases and irregular 5 cases. Surgical management is the standard procedure for treatment of phyllodes tumors. A wide local excision was performed in 147 cases, mastectomy in 20 cases (modified radical mastectomy in 2 cases) and wide excision followed by mastectomy 21 cases. The final pathological diagnoses of the phyllodes tumors were: benign 118 cases (62%), borderline 33 cases (18%) and malignant in 37 cases (20%). The margin did not affect recurrence in all types.Conclusion: The most frequent is a benign phyllodes tumor. Surgical treatment to remove the tumor with a free margin is acceptable with no recurrence difference from a wider margin. However, younger age and malignant phyllodes tumor are the two highest risk factors for recurrence.Keywords: phyllodes tumor, breast, surgical margin |
| first_indexed | 2024-04-14T01:39:01Z |
| format | Article |
| id | doaj.art-ec6cf4ba146649fab85bc40cbab0d8c3 |
| institution | Directory Open Access Journal |
| issn | 1179-1322 |
| language | English |
| last_indexed | 2024-04-14T01:39:01Z |
| publishDate | 2019-08-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Cancer Management and Research |
| spelling | doaj.art-ec6cf4ba146649fab85bc40cbab0d8c32022-12-22T02:19:50ZengDove Medical PressCancer Management and Research1179-13222019-08-01Volume 117805781147956Phyllodes tumor of the breast: diagnosis, management and outcome during a 10-year experienceDitsatham CChongruksut WChagkrit Ditsatham,1 Wilaiwan Chongruksut21Division of Head, Neck, and Breast Surgery, Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand; 2Research Unit, Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, ThailandCorrespondence: Chagkrit DitsathamDepartment of Surgery, Faculty of Medicine, Chiang Mai University, 110 Intavaroros Road, Amphoe Muang, Chiang Mai 50200, ThailandTel +66 5 394 5532Fax +66 5 394 6139Email nansurg7@gmail.comBackground: Phyllodes tumor is a very rare tumor of the breast, incidence being 0.3–0.9% of all breast tumors. Phyllodes tumors are classified into three grades: benign, borderline or malignant. The aim of this study was to investigate patient characteristics, imaging characteristic findings, surgical treatment and outcome of phyllodes tumor.Materials and methods: This is a retrospective review of phyllodes tumor patients who had undergone surgical management between 1 January 2006 and 31 December 2015 in Head, Neck and Breast Unit, Department of Surgery, Chiang Mai University Hospital.Results: A total of 188 phyllodes tumor patients were included in this study. The average age of the patients was 35.6 years. The majority of the tumors were of lobulated shape. Tumor morphology from imaging: lobulated shaped tumor 112 cases, oval-shape 37 cases, round shape 8 cases and irregular 5 cases. Surgical management is the standard procedure for treatment of phyllodes tumors. A wide local excision was performed in 147 cases, mastectomy in 20 cases (modified radical mastectomy in 2 cases) and wide excision followed by mastectomy 21 cases. The final pathological diagnoses of the phyllodes tumors were: benign 118 cases (62%), borderline 33 cases (18%) and malignant in 37 cases (20%). The margin did not affect recurrence in all types.Conclusion: The most frequent is a benign phyllodes tumor. Surgical treatment to remove the tumor with a free margin is acceptable with no recurrence difference from a wider margin. However, younger age and malignant phyllodes tumor are the two highest risk factors for recurrence.Keywords: phyllodes tumor, breast, surgical marginhttps://www.dovepress.com/phyllodes-tumor-of-the-breast-diagnosis-management-and-outcome-during--peer-reviewed-article-CMARphyllodes tumorbreastsurgical margin |
| spellingShingle | Ditsatham C Chongruksut W Phyllodes tumor of the breast: diagnosis, management and outcome during a 10-year experience Cancer Management and Research phyllodes tumor breast surgical margin |
| title | Phyllodes tumor of the breast: diagnosis, management and outcome during a 10-year experience |
| title_full | Phyllodes tumor of the breast: diagnosis, management and outcome during a 10-year experience |
| title_fullStr | Phyllodes tumor of the breast: diagnosis, management and outcome during a 10-year experience |
| title_full_unstemmed | Phyllodes tumor of the breast: diagnosis, management and outcome during a 10-year experience |
| title_short | Phyllodes tumor of the breast: diagnosis, management and outcome during a 10-year experience |
| title_sort | phyllodes tumor of the breast diagnosis management and outcome during a 10 year experience |
| topic | phyllodes tumor breast surgical margin |
| url | https://www.dovepress.com/phyllodes-tumor-of-the-breast-diagnosis-management-and-outcome-during--peer-reviewed-article-CMAR |
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