Murine model of elastase-induced proximal thoracic aortic aneurysm through a midline incision in the anterior neck

Murine model of elastase-induced proximal thoracic aortic aneurysm through a midline incision in the anterior neck

ObjectiveThis study was performed to develop a murine model of elastase-induced proximal thoracic aortic aneurysms (PTAAs).MethodsThe ascending thoracic aorta and aortic arch of adult C57BL/6J male mice were exposed through a midline incision in the anterior neck, followed by peri-adventitial elasta...

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Bibliographic Details
Main Authors: Jianqing Deng, Dandan Li, Xuelin Zhang, Weihang Lu, Dan Rong, Xinhao Wang, Guoyi Sun, Senhao Jia, Hongpeng Zhang, Xin Jia, Wei Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
thoracic aortic aneurysm
experimental models
aneurysmal pathology
elastase
aortic degenerative disease
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.953514/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2023.953514/full

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