Antibacterial Potential of the Extracts of the Leaves of Azadirachta indica Linn.

Azadirachta indica A. Juss (syn. Melia azadirachta) is well known in India and popularly known as Indian neem. To evaluate antibacterial potential, the agar well diffusion assay was used against Gram-negative and Gram-positive bacteria. Penicillin and Dimethyl sulfoxide were used as positive and neg...

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Main Authors: Saradhajyothi KOONA, Subbarao BUDIDA
Format: Article
Language:English
Published: Society of Land Measurements and Cadastre from Transylvania (SMTCT) 2011-03-01
Series:Notulae Scientia Biologicae
Online Access:http://www.notulaebiologicae.ro/index.php/nsb/article/view/5470
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author Saradhajyothi KOONA
Subbarao BUDIDA
author_facet Saradhajyothi KOONA
Subbarao BUDIDA
author_sort Saradhajyothi KOONA
collection DOAJ
description Azadirachta indica A. Juss (syn. Melia azadirachta) is well known in India and popularly known as Indian neem. To evaluate antibacterial potential, the agar well diffusion assay was used against Gram-negative and Gram-positive bacteria. Penicillin and Dimethyl sulfoxide were used as positive and negative controls, respectively. Methanol extract showed the highest and chloroform extract showed moderate to good antibacterial activity. Proteus vulgaris and Micrococcus luteus were the most susceptible bacteria while Bacillus subtilis was more resistant bacterium to the hexane, chloroform and methanol extracts of neem. The study recommended for the isolation and separation of bioactive compounds responsible for the antibacterial activity.
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spelling doaj.art-ec71e6dca7ca437f839d7de83c8a517b2022-12-22T02:07:08ZengSociety of Land Measurements and Cadastre from Transylvania (SMTCT)Notulae Scientia Biologicae2067-32052067-32642011-03-0131656910.15835/nsb3154705731Antibacterial Potential of the Extracts of the Leaves of Azadirachta indica Linn.Saradhajyothi KOONA0Subbarao BUDIDA1Department of Botany, Andhra University, Visakhapatnam-530 003(A.P)Department of Botany, Andhra University, Visakhapatnam-530 003(A.P)Azadirachta indica A. Juss (syn. Melia azadirachta) is well known in India and popularly known as Indian neem. To evaluate antibacterial potential, the agar well diffusion assay was used against Gram-negative and Gram-positive bacteria. Penicillin and Dimethyl sulfoxide were used as positive and negative controls, respectively. Methanol extract showed the highest and chloroform extract showed moderate to good antibacterial activity. Proteus vulgaris and Micrococcus luteus were the most susceptible bacteria while Bacillus subtilis was more resistant bacterium to the hexane, chloroform and methanol extracts of neem. The study recommended for the isolation and separation of bioactive compounds responsible for the antibacterial activity.http://www.notulaebiologicae.ro/index.php/nsb/article/view/5470
spellingShingle Saradhajyothi KOONA
Subbarao BUDIDA
Antibacterial Potential of the Extracts of the Leaves of Azadirachta indica Linn.
Notulae Scientia Biologicae
title Antibacterial Potential of the Extracts of the Leaves of Azadirachta indica Linn.
title_full Antibacterial Potential of the Extracts of the Leaves of Azadirachta indica Linn.
title_fullStr Antibacterial Potential of the Extracts of the Leaves of Azadirachta indica Linn.
title_full_unstemmed Antibacterial Potential of the Extracts of the Leaves of Azadirachta indica Linn.
title_short Antibacterial Potential of the Extracts of the Leaves of Azadirachta indica Linn.
title_sort antibacterial potential of the extracts of the leaves of azadirachta indica linn
url http://www.notulaebiologicae.ro/index.php/nsb/article/view/5470
work_keys_str_mv AT saradhajyothikoona antibacterialpotentialoftheextractsoftheleavesofazadirachtaindicalinn
AT subbaraobudida antibacterialpotentialoftheextractsoftheleavesofazadirachtaindicalinn