INTERNATIONAL PRACTICE OF ABATACEPT USE IN TREATMENT OF REFRACTORY UVEITIS IN PATIENTS WITH IDIOPATHIC JUVENILE ARTHRITIS
<em>The article contains analysis of international practice of abatacept use in treatment of refractory uveitis in patients with idiopathic juvenile rheumatoid arthritis. Efficacy of T-cell co-stimulation blockade in treatment of severe autoimmune fontal uveitis has been proven on the models....
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| Format: | Article |
| Language: | English |
| Published: |
"Paediatrician" Publishers LLC
2011-01-01
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| Series: | Вопросы современной педиатрии |
| Online Access: | http://vsp.spr-journal.ru:80/jour/article/view/665 |
| _version_ | 1797766207839928320 |
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| author | R.V. Denisova E.I. Alexeeva |
| author_facet | R.V. Denisova E.I. Alexeeva |
| author_sort | R.V. Denisova |
| collection | DOAJ |
| description | <em>The article contains analysis of international practice of abatacept use in treatment of refractory uveitis in patients with idiopathic juvenile rheumatoid arthritis. Efficacy of T-cell co-stimulation blockade in treatment of severe autoimmune fontal uveitis has been proven on the models. Described clinical cases show that, abatacept is an effective and well tolerated biological drug, that allows achieving success in treatment even after proven inefficacy and intolerance of traditional immunosuppressants and TNF α antagonists. Shown results testify to availability of a abatacept treatment of a refractory uveitis in patients with juvenile idiopathic rheumatoid arthritis and the necessity of further efficacy and tolerance research with protracted therapeutic schemes.</em><br /> <strong><em>Key words: children, juvenile idiopathic arthritis, uveitis, treatment, abatacept, lymphocyte co-stimulation blockade, biological treatment.</em></strong><strong> </strong><br /> <em><span style="text-decoration: underline;">(<em><span><em><em><em>Voprosy sovremennoi pediatrii — </em></em></em></span></em></span></em><em><span style="text-decoration: underline;">Current Pediatrics. — 2011; 10 (5): 39–44.)</span></em> |
| first_indexed | 2024-03-12T20:20:56Z |
| format | Article |
| id | doaj.art-ec72b5481025445f82b33fa9ca8fc975 |
| institution | Directory Open Access Journal |
| issn | 1682-5527 1682-5535 |
| language | English |
| last_indexed | 2024-03-12T20:20:56Z |
| publishDate | 2011-01-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj.art-ec72b5481025445f82b33fa9ca8fc9752023-08-02T00:59:01Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352011-01-011053944665INTERNATIONAL PRACTICE OF ABATACEPT USE IN TREATMENT OF REFRACTORY UVEITIS IN PATIENTS WITH IDIOPATHIC JUVENILE ARTHRITISR.V. Denisova0E.I. Alexeeva1Scientific Center of Children’s Health RAMS, MoscowScientific Center of Children’s Health RAMS, Moscow Sechenov First Moscow State Medical University<em>The article contains analysis of international practice of abatacept use in treatment of refractory uveitis in patients with idiopathic juvenile rheumatoid arthritis. Efficacy of T-cell co-stimulation blockade in treatment of severe autoimmune fontal uveitis has been proven on the models. Described clinical cases show that, abatacept is an effective and well tolerated biological drug, that allows achieving success in treatment even after proven inefficacy and intolerance of traditional immunosuppressants and TNF α antagonists. Shown results testify to availability of a abatacept treatment of a refractory uveitis in patients with juvenile idiopathic rheumatoid arthritis and the necessity of further efficacy and tolerance research with protracted therapeutic schemes.</em><br /> <strong><em>Key words: children, juvenile idiopathic arthritis, uveitis, treatment, abatacept, lymphocyte co-stimulation blockade, biological treatment.</em></strong><strong> </strong><br /> <em><span style="text-decoration: underline;">(<em><span><em><em><em>Voprosy sovremennoi pediatrii — </em></em></em></span></em></span></em><em><span style="text-decoration: underline;">Current Pediatrics. — 2011; 10 (5): 39–44.)</span></em>http://vsp.spr-journal.ru:80/jour/article/view/665 |
| spellingShingle | R.V. Denisova E.I. Alexeeva INTERNATIONAL PRACTICE OF ABATACEPT USE IN TREATMENT OF REFRACTORY UVEITIS IN PATIENTS WITH IDIOPATHIC JUVENILE ARTHRITIS Вопросы современной педиатрии |
| title | INTERNATIONAL PRACTICE OF ABATACEPT USE IN TREATMENT OF REFRACTORY UVEITIS IN PATIENTS WITH IDIOPATHIC JUVENILE ARTHRITIS |
| title_full | INTERNATIONAL PRACTICE OF ABATACEPT USE IN TREATMENT OF REFRACTORY UVEITIS IN PATIENTS WITH IDIOPATHIC JUVENILE ARTHRITIS |
| title_fullStr | INTERNATIONAL PRACTICE OF ABATACEPT USE IN TREATMENT OF REFRACTORY UVEITIS IN PATIENTS WITH IDIOPATHIC JUVENILE ARTHRITIS |
| title_full_unstemmed | INTERNATIONAL PRACTICE OF ABATACEPT USE IN TREATMENT OF REFRACTORY UVEITIS IN PATIENTS WITH IDIOPATHIC JUVENILE ARTHRITIS |
| title_short | INTERNATIONAL PRACTICE OF ABATACEPT USE IN TREATMENT OF REFRACTORY UVEITIS IN PATIENTS WITH IDIOPATHIC JUVENILE ARTHRITIS |
| title_sort | international practice of abatacept use in treatment of refractory uveitis in patients with idiopathic juvenile arthritis |
| url | http://vsp.spr-journal.ru:80/jour/article/view/665 |
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