Brain but not serum BDNF levels are associated with structural alterations in the hippocampal regions in patients with drug-resistant mesial temporal lobe epilepsy

Brain but not serum BDNF levels are associated with structural alterations in the hippocampal regions in patients with drug-resistant mesial temporal lobe epilepsy

Mesial temporal lobe epilepsy is the most common type of focal epilepsy, imposing a significant burden on the health care system worldwide. Approximately one-third of patients with this disease who do not adequately respond to pharmacotherapy are considered drug-resistant subjects. Despite having so...

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Bibliographic Details
Main Authors: Elena A. Filimonova, Anton A. Pashkov, Galina I. Moysak, Anastasia Y. Tropynina, Svetlana Y. Zhanaeva, Anna A. Shvaikovskaya, Anna A. Akopyan, Konstantin V. Danilenko, Lyubomir I. Aftanas, Maria A. Tikhonova, Jamil A. Rzaev
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Neuroscience
Subjects:
mesial temporal lobe epilepsy
drug-resistant epilepsy
BDNF
MR morphometry
FreeSurfer
hippocampus
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1217702/full

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