Adverse childhood experience and asthma onset: a systematic review
Adverse childhood experiences such as abuse and neglect are associated with subsequent immune dysregulation. Some studies show an association between adverse childhood experiences and asthma onset, although significant disparity in results exists in the published literature. We aimed to review avail...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
European Respiratory Society
2015-06-01
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| Series: | European Respiratory Review |
| Online Access: | http://err.ersjournals.com/content/24/136/299.full |
| _version_ | 1828302958358429696 |
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| author | Daniel Exley Alyson Norman Michael Hyland |
| author_facet | Daniel Exley Alyson Norman Michael Hyland |
| author_sort | Daniel Exley |
| collection | DOAJ |
| description | Adverse childhood experiences such as abuse and neglect are associated with subsequent immune dysregulation. Some studies show an association between adverse childhood experiences and asthma onset, although significant disparity in results exists in the published literature. We aimed to review available studies employing a prospective design that investigates associations between adverse childhood experience and asthma. A search protocol was developed and studies were drawn from four electronic journal databases. Studies were selected in accordance with pre-set inclusion criteria and relevant data were extracted. 12 studies, assessing data from a total of 31 524 individuals, were identified that investigate the impact of a range of adverse childhood experiences on the likelihood of developing asthma. Evidence suggests that chronic stress exposure and maternal distress in pregnancy operate synergistically with known triggers such as traffic-related air pollution to increase asthma risk. Chronic stress in early life is associated with an increased risk of asthma onset. There is evidence that adverse childhood experience increases the impact of traffic-related air pollution and inconsistent evidence that adverse childhood experience has an independent effect on asthma onset. |
| first_indexed | 2024-04-13T13:45:09Z |
| format | Article |
| id | doaj.art-ec772039d2b64a2d83136a7a644c1190 |
| institution | Directory Open Access Journal |
| issn | 0905-9180 1600-0617 |
| language | English |
| last_indexed | 2024-04-13T13:45:09Z |
| publishDate | 2015-06-01 |
| publisher | European Respiratory Society |
| record_format | Article |
| series | European Respiratory Review |
| spelling | doaj.art-ec772039d2b64a2d83136a7a644c11902022-12-22T02:44:30ZengEuropean Respiratory SocietyEuropean Respiratory Review0905-91801600-06172015-06-012413629930510.1183/16000617.0000411404114Adverse childhood experience and asthma onset: a systematic reviewDaniel Exley0Alyson Norman1Michael Hyland2 School of Psychology, University of Plymouth, Plymouth, UK School of Psychology, University of Plymouth, Plymouth, UK School of Psychology, University of Plymouth, Plymouth, UK Adverse childhood experiences such as abuse and neglect are associated with subsequent immune dysregulation. Some studies show an association between adverse childhood experiences and asthma onset, although significant disparity in results exists in the published literature. We aimed to review available studies employing a prospective design that investigates associations between adverse childhood experience and asthma. A search protocol was developed and studies were drawn from four electronic journal databases. Studies were selected in accordance with pre-set inclusion criteria and relevant data were extracted. 12 studies, assessing data from a total of 31 524 individuals, were identified that investigate the impact of a range of adverse childhood experiences on the likelihood of developing asthma. Evidence suggests that chronic stress exposure and maternal distress in pregnancy operate synergistically with known triggers such as traffic-related air pollution to increase asthma risk. Chronic stress in early life is associated with an increased risk of asthma onset. There is evidence that adverse childhood experience increases the impact of traffic-related air pollution and inconsistent evidence that adverse childhood experience has an independent effect on asthma onset.http://err.ersjournals.com/content/24/136/299.full |
| spellingShingle | Daniel Exley Alyson Norman Michael Hyland Adverse childhood experience and asthma onset: a systematic review European Respiratory Review |
| title | Adverse childhood experience and asthma onset: a systematic review |
| title_full | Adverse childhood experience and asthma onset: a systematic review |
| title_fullStr | Adverse childhood experience and asthma onset: a systematic review |
| title_full_unstemmed | Adverse childhood experience and asthma onset: a systematic review |
| title_short | Adverse childhood experience and asthma onset: a systematic review |
| title_sort | adverse childhood experience and asthma onset a systematic review |
| url | http://err.ersjournals.com/content/24/136/299.full |
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