Frequency distribution of HCV resistance-associated variants in infected patients treated with direct-acting antivirals

Frequency distribution of HCV resistance-associated variants in infected patients treated with direct-acting antivirals

ABSTRACT: Background: Hepatitis C virus (HCV) is a global public health problem. Second-generation direct-acting antivirals targeting non-structural regions on the viral genome are the cornerstone for treatment of chronic infection. However, resistance-associated variants (RAVs) have been reported...

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Main Authors: Bianca Catarina Azeredo Cabral, Juliene Antonio Ramos, Amanda Laryssa de Melo Silveira, Érica Ramos dos Santos Nascimento, Selma Baía Ferreira, Henrique Sérgio Moraes Coelho, Rodrigo Soares Moura-Neto, Cristiane Alves Villela-Nogueira, Luísa Hoffmann, Rosane Silva
Format: Article
Language:English
Published: Elsevier 2022-02-01
Series:International Journal of Infectious Diseases
Subjects:
Hepatitis C
Massively parallel sequencing
RAVs
Treatment response
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971221012170

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