Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases
Rajasekharreddy Pala,1,2 VT Anju,3 Madhu Dyavaiah,3 Siddhardha Busi,4 Surya M Nauli1,2 1Department of Biomedical and Pharmaceutical Sciences, Harry and Diane Rinker Health Science Campus, Chapman University, Irvine, CA 92618, USA; 2Department of Medicine, University of California Irvine, Irvine, CA...
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Format: | Article |
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Dove Medical Press
2020-05-01
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Series: | International Journal of Nanomedicine |
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Online Access: | https://www.dovepress.com/nanoparticle-mediated-drug-delivery-for-the-treatment-of-cardiovascula-peer-reviewed-article-IJN |
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author | Pala R Anju VT Dyavaiah M Busi S Nauli SM |
author_facet | Pala R Anju VT Dyavaiah M Busi S Nauli SM |
author_sort | Pala R |
collection | DOAJ |
description | Rajasekharreddy Pala,1,2 VT Anju,3 Madhu Dyavaiah,3 Siddhardha Busi,4 Surya M Nauli1,2 1Department of Biomedical and Pharmaceutical Sciences, Harry and Diane Rinker Health Science Campus, Chapman University, Irvine, CA 92618, USA; 2Department of Medicine, University of California Irvine, Irvine, CA 92868, USA; 3Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Puducherry, India; 4Department of Microbiology, School of Life Sciences, Pondicherry University, Puducherry, IndiaCorrespondence: Rajasekharreddy Pala; Surya M Nauli Tel +714-516-5462; +714-516-5480Fax +714-516-5481Email rrpala@chapman.edu; nauli@chapman.eduAbstract: Cardiovascular diseases (CVDs) are one of the foremost causes of high morbidity and mortality globally. Preventive, diagnostic, and treatment measures available for CVDs are not very useful, which demands promising alternative methods. Nanoscience and nanotechnology open a new window in the area of CVDs with an opportunity to achieve effective treatment, better prognosis, and less adverse effects on non-target tissues. The application of nanoparticles and nanocarriers in the area of cardiology has gathered much attention due to the properties such as passive and active targeting to the cardiac tissues, improved target specificity, and sensitivity. It has reported that more than 50% of CVDs can be treated effectively through the use of nanotechnology. The main goal of this review is to explore the recent advancements in nanoparticle-based cardiovascular drug carriers. This review also summarizes the difficulties associated with the conventional treatment modalities in comparison to the nanomedicine for CVDs.Keywords: cardiovascular diseases, nanoscience, nanoparticles, nanomedicine, nanocarriers, treatment |
first_indexed | 2024-12-19T05:09:41Z |
format | Article |
id | doaj.art-ec7d102a161743fd97cb171439f43615 |
institution | Directory Open Access Journal |
issn | 1178-2013 |
language | English |
last_indexed | 2024-12-19T05:09:41Z |
publishDate | 2020-05-01 |
publisher | Dove Medical Press |
record_format | Article |
series | International Journal of Nanomedicine |
spelling | doaj.art-ec7d102a161743fd97cb171439f436152022-12-21T20:34:50ZengDove Medical PressInternational Journal of Nanomedicine1178-20132020-05-01Volume 153741376954115Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular DiseasesPala RAnju VTDyavaiah MBusi SNauli SMRajasekharreddy Pala,1,2 VT Anju,3 Madhu Dyavaiah,3 Siddhardha Busi,4 Surya M Nauli1,2 1Department of Biomedical and Pharmaceutical Sciences, Harry and Diane Rinker Health Science Campus, Chapman University, Irvine, CA 92618, USA; 2Department of Medicine, University of California Irvine, Irvine, CA 92868, USA; 3Department of Biochemistry and Molecular Biology, School of Life Sciences, Pondicherry University, Puducherry, India; 4Department of Microbiology, School of Life Sciences, Pondicherry University, Puducherry, IndiaCorrespondence: Rajasekharreddy Pala; Surya M Nauli Tel +714-516-5462; +714-516-5480Fax +714-516-5481Email rrpala@chapman.edu; nauli@chapman.eduAbstract: Cardiovascular diseases (CVDs) are one of the foremost causes of high morbidity and mortality globally. Preventive, diagnostic, and treatment measures available for CVDs are not very useful, which demands promising alternative methods. Nanoscience and nanotechnology open a new window in the area of CVDs with an opportunity to achieve effective treatment, better prognosis, and less adverse effects on non-target tissues. The application of nanoparticles and nanocarriers in the area of cardiology has gathered much attention due to the properties such as passive and active targeting to the cardiac tissues, improved target specificity, and sensitivity. It has reported that more than 50% of CVDs can be treated effectively through the use of nanotechnology. The main goal of this review is to explore the recent advancements in nanoparticle-based cardiovascular drug carriers. This review also summarizes the difficulties associated with the conventional treatment modalities in comparison to the nanomedicine for CVDs.Keywords: cardiovascular diseases, nanoscience, nanoparticles, nanomedicine, nanocarriers, treatmenthttps://www.dovepress.com/nanoparticle-mediated-drug-delivery-for-the-treatment-of-cardiovascula-peer-reviewed-article-IJNcardiovascular diseasesnanosciencenanoparticlesnanomedicinenanocarrierstreatment |
spellingShingle | Pala R Anju VT Dyavaiah M Busi S Nauli SM Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases International Journal of Nanomedicine cardiovascular diseases nanoscience nanoparticles nanomedicine nanocarriers treatment |
title | Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases |
title_full | Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases |
title_fullStr | Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases |
title_full_unstemmed | Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases |
title_short | Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases |
title_sort | nanoparticle mediated drug delivery for the treatment of cardiovascular diseases |
topic | cardiovascular diseases nanoscience nanoparticles nanomedicine nanocarriers treatment |
url | https://www.dovepress.com/nanoparticle-mediated-drug-delivery-for-the-treatment-of-cardiovascula-peer-reviewed-article-IJN |
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