One-year follow-up of the effects of sildenafil on pulmonary arterial hypertension and veno-occlusive disease

One-year follow-up of the effects of sildenafil on pulmonary arterial hypertension and veno-occlusive disease

We hypothesized that chronic oral administration of the phosphodiesterase-5 inhibitor sildenafil could improve the exercise capacity and pulmonary hemodynamics in patients with pulmonary arterial hypertension (PAH) on the basis of previous short-term studies. We tested this hypothesis in 14 subjects...

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Bibliographic Details
Main Authors: A.C. Barreto, S.M. Franchi, C.R.P. Castro, A.A. Lopes
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2005-02-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Sildenafil
Pulmonary hypertension
Pulmonary veno-occlusive disease
Phosphodiesterase inhibitors
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000200006

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