Characterization of Sialic Acid-Binding Immunoglobulin-Type Lectins in Fish Reveals Teleost-Specific Structures and Expression Patterns

Characterization of Sialic Acid-Binding Immunoglobulin-Type Lectins in Fish Reveals Teleost-Specific Structures and Expression Patterns

The cellular glycocalyx of vertebrates is frequently decorated with sialic acid residues. These sialylated structures are recognized by sialic acid-binding immunoglobulin-type lectins (Siglecs) of immune cells, which modulate their responsiveness. Fifteen Siglecs are known to be expressed in humans,...

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Bibliographic Details
Main Authors: Kim F. Bornhöfft, Joan Martorell Ribera, Torsten Viergutz, Marzia T. Venuto, Ulrike Gimsa, Sebastian P. Galuska, Alexander Rebl
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cells
Subjects:
acute stress
ITIM
Salmonidae
siglecs
sialic acids
vertebrate evolution
Online Access:https://www.mdpi.com/2073-4409/9/4/836

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