A rare case of cerebellar pilomyxoid astrocytoma associated with neurofibromatosis-1 in a young female; case report highlighting immunohistochemical features
Pilomyxoid astrocytoma (PMA), a distinct clinico-histopathological entity in the World Health Organization classification 2007, tends to be locally aggressive, with higher chance of leptomeningeal dissemination, recurrence, and poor prognosis. PMA is generally seen in young children and tend to occu...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | Indian Journal of Pathology and Microbiology |
| Subjects: | |
| Online Access: | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2021;volume=64;issue=2;spage=354;epage=357;aulast=Sinai |
| _version_ | 1831538384415227904 |
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| author | Siddhi Gaurish Sinai Khandeparkar Shital Subhash Gosavi Bageshri P Gogate Nikhil Talathi |
| author_facet | Siddhi Gaurish Sinai Khandeparkar Shital Subhash Gosavi Bageshri P Gogate Nikhil Talathi |
| author_sort | Siddhi Gaurish Sinai Khandeparkar |
| collection | DOAJ |
| description | Pilomyxoid astrocytoma (PMA), a distinct clinico-histopathological entity in the World Health Organization classification 2007, tends to be locally aggressive, with higher chance of leptomeningeal dissemination, recurrence, and poor prognosis. PMA is generally seen in young children and tend to occur in the hypothalamic-chiasmatic region. Their presence in other parts of the brain in the non pediatric age group is uncommon. To the best of our knowledge we are presenting first case of cerebellar PMA associated with neurofibromatosis 1 (NF1) in a 40-year- old female, with immunohistochemical study. |
| first_indexed | 2024-12-16T23:22:49Z |
| format | Article |
| id | doaj.art-ec8298539e7647a4a6f1a8d3ab9a0aa1 |
| institution | Directory Open Access Journal |
| issn | 0377-4929 |
| language | English |
| last_indexed | 2024-12-16T23:22:49Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj.art-ec8298539e7647a4a6f1a8d3ab9a0aa12022-12-21T22:12:07ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292021-01-0164235435710.4103/IJPM.IJPM_209_20A rare case of cerebellar pilomyxoid astrocytoma associated with neurofibromatosis-1 in a young female; case report highlighting immunohistochemical featuresSiddhi Gaurish Sinai KhandeparkarShital Subhash GosaviBageshri P GogateNikhil TalathiPilomyxoid astrocytoma (PMA), a distinct clinico-histopathological entity in the World Health Organization classification 2007, tends to be locally aggressive, with higher chance of leptomeningeal dissemination, recurrence, and poor prognosis. PMA is generally seen in young children and tend to occur in the hypothalamic-chiasmatic region. Their presence in other parts of the brain in the non pediatric age group is uncommon. To the best of our knowledge we are presenting first case of cerebellar PMA associated with neurofibromatosis 1 (NF1) in a 40-year- old female, with immunohistochemical study.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2021;volume=64;issue=2;spage=354;epage=357;aulast=Sinaicerebellumgfapnf-1pilomyxoid astrocytoma |
| spellingShingle | Siddhi Gaurish Sinai Khandeparkar Shital Subhash Gosavi Bageshri P Gogate Nikhil Talathi A rare case of cerebellar pilomyxoid astrocytoma associated with neurofibromatosis-1 in a young female; case report highlighting immunohistochemical features Indian Journal of Pathology and Microbiology cerebellum gfap nf-1 pilomyxoid astrocytoma |
| title | A rare case of cerebellar pilomyxoid astrocytoma associated with neurofibromatosis-1 in a young female; case report highlighting immunohistochemical features |
| title_full | A rare case of cerebellar pilomyxoid astrocytoma associated with neurofibromatosis-1 in a young female; case report highlighting immunohistochemical features |
| title_fullStr | A rare case of cerebellar pilomyxoid astrocytoma associated with neurofibromatosis-1 in a young female; case report highlighting immunohistochemical features |
| title_full_unstemmed | A rare case of cerebellar pilomyxoid astrocytoma associated with neurofibromatosis-1 in a young female; case report highlighting immunohistochemical features |
| title_short | A rare case of cerebellar pilomyxoid astrocytoma associated with neurofibromatosis-1 in a young female; case report highlighting immunohistochemical features |
| title_sort | rare case of cerebellar pilomyxoid astrocytoma associated with neurofibromatosis 1 in a young female case report highlighting immunohistochemical features |
| topic | cerebellum gfap nf-1 pilomyxoid astrocytoma |
| url | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2021;volume=64;issue=2;spage=354;epage=357;aulast=Sinai |
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