The comparison of efficacy and safety between transradial and transfemoral approach for chronic total occlusions intervention: a meta-analysis
Abstract This meta-analysis compared the outcomes of transradial access (TRA) and transfemoral access (TFA) in chronic total occlusion (CTO) percutaneous coronary intervention (PCI) in recent decades. We searched multiple databases for articles published between January 1, 2015, and December 31, 202...
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| Format: | Article |
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Nature Portfolio
2022-05-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-11763-y |
| _version_ | 1818203768443895808 |
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| author | Wei-Chieh Lee Po-Jui Wu Chih-Yuan Fang Hsiu-Yu Fang Chiung-Jen Wu Ping-Yen Liu |
| author_facet | Wei-Chieh Lee Po-Jui Wu Chih-Yuan Fang Hsiu-Yu Fang Chiung-Jen Wu Ping-Yen Liu |
| author_sort | Wei-Chieh Lee |
| collection | DOAJ |
| description | Abstract This meta-analysis compared the outcomes of transradial access (TRA) and transfemoral access (TFA) in chronic total occlusion (CTO) percutaneous coronary intervention (PCI) in recent decades. We searched multiple databases for articles published between January 1, 2015, and December 31, 2020. Six observational studies with 11,736 patients were analyzed. Data included baseline demographics, Japan-chronic total occlusion (J-CTO) score, sheath size, PCI vessel, retrograde method, procedural time, fluoroscopy time, and contrast volume. The more prevalent target CTO vessel was the left coronary artery in the TRA group and the right coronary artery in the TFA group. Higher J-CTO score, longer procedural time, and more contrast volume were seen in the TFA group. In comparison, the TRA group had better procedural success rate (odds ratio (OR), 0.846; 95% confidence interval (CI) 0.749–0.956) and less vascular complications (OR, 0.323; 95% CI 0.203–0.515), but similar retrograde success rate (OR, 0.965; 95% CI 0.382–2.435). In-hospital death (OR, 0.527; 95% CI 0.187–1.489) and major adverse cardiovascular events (OR, 0.729; 95% CI 0.504–1.054) did not differ between the groups. Overall, fewer vascular complications and higher procedural success rates were noted in the TRA CTO PCI population. However, similar retrograde success rates and clinical outcomes were noted between the groups. |
| first_indexed | 2024-12-12T03:30:35Z |
| format | Article |
| id | doaj.art-ec830ef2d41948f8aafe4997cb209a61 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-12T03:30:35Z |
| publishDate | 2022-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-ec830ef2d41948f8aafe4997cb209a612022-12-22T00:39:56ZengNature PortfolioScientific Reports2045-23222022-05-011211810.1038/s41598-022-11763-yThe comparison of efficacy and safety between transradial and transfemoral approach for chronic total occlusions intervention: a meta-analysisWei-Chieh Lee0Po-Jui Wu1Chih-Yuan Fang2Hsiu-Yu Fang3Chiung-Jen Wu4Ping-Yen Liu5Institute of Clinical Medicine, College of Medicine, National Cheng Kung UniversityDivision of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of MedicineDivision of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of MedicineDivision of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of MedicineDivision of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of MedicineInstitute of Clinical Medicine, College of Medicine, National Cheng Kung UniversityAbstract This meta-analysis compared the outcomes of transradial access (TRA) and transfemoral access (TFA) in chronic total occlusion (CTO) percutaneous coronary intervention (PCI) in recent decades. We searched multiple databases for articles published between January 1, 2015, and December 31, 2020. Six observational studies with 11,736 patients were analyzed. Data included baseline demographics, Japan-chronic total occlusion (J-CTO) score, sheath size, PCI vessel, retrograde method, procedural time, fluoroscopy time, and contrast volume. The more prevalent target CTO vessel was the left coronary artery in the TRA group and the right coronary artery in the TFA group. Higher J-CTO score, longer procedural time, and more contrast volume were seen in the TFA group. In comparison, the TRA group had better procedural success rate (odds ratio (OR), 0.846; 95% confidence interval (CI) 0.749–0.956) and less vascular complications (OR, 0.323; 95% CI 0.203–0.515), but similar retrograde success rate (OR, 0.965; 95% CI 0.382–2.435). In-hospital death (OR, 0.527; 95% CI 0.187–1.489) and major adverse cardiovascular events (OR, 0.729; 95% CI 0.504–1.054) did not differ between the groups. Overall, fewer vascular complications and higher procedural success rates were noted in the TRA CTO PCI population. However, similar retrograde success rates and clinical outcomes were noted between the groups.https://doi.org/10.1038/s41598-022-11763-y |
| spellingShingle | Wei-Chieh Lee Po-Jui Wu Chih-Yuan Fang Hsiu-Yu Fang Chiung-Jen Wu Ping-Yen Liu The comparison of efficacy and safety between transradial and transfemoral approach for chronic total occlusions intervention: a meta-analysis Scientific Reports |
| title | The comparison of efficacy and safety between transradial and transfemoral approach for chronic total occlusions intervention: a meta-analysis |
| title_full | The comparison of efficacy and safety between transradial and transfemoral approach for chronic total occlusions intervention: a meta-analysis |
| title_fullStr | The comparison of efficacy and safety between transradial and transfemoral approach for chronic total occlusions intervention: a meta-analysis |
| title_full_unstemmed | The comparison of efficacy and safety between transradial and transfemoral approach for chronic total occlusions intervention: a meta-analysis |
| title_short | The comparison of efficacy and safety between transradial and transfemoral approach for chronic total occlusions intervention: a meta-analysis |
| title_sort | comparison of efficacy and safety between transradial and transfemoral approach for chronic total occlusions intervention a meta analysis |
| url | https://doi.org/10.1038/s41598-022-11763-y |
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