Proinflammatory and Cancer-Promoting Pathobiont <i>Fusobacterium nucleatum</i> Directly Targets Colorectal Cancer Stem Cells

Proinflammatory and Cancer-Promoting Pathobiont <i>Fusobacterium nucleatum</i> Directly Targets Colorectal Cancer Stem Cells

Intestinal bacterial communities participate in gut homeostasis and are recognized as crucial in bowel inflammation and colorectal cancer (CRC). <i>Fusobacterium nucleatum</i> (<i>Fn</i>), a pathobiont of the oral microflora, has recently emerged as a CRC-associated microbe l...

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Bibliographic Details
Main Authors: Virve Cavallucci, Ivana Palucci, Marco Fidaleo, Antonella Mercuri, Letizia Masi, Valeria Emoli, Giada Bianchetti, Micol Eleonora Fiori, Gilad Bachrach, Franco Scaldaferri, Giuseppe Maulucci, Giovanni Delogu, Giovambattista Pani
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biomolecules
Subjects:
colorectal cancer
cancer stem cells
microbiota
fusobacterium nucleatum
tumor microenvironment
tumor spheroids
Online Access:https://www.mdpi.com/2218-273X/12/9/1256

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