MICRO-RNA – A Potential Biomarker In Cancer

MicroRNA (miRNA) is the class of short non-coding RNA, about 21 nucleotides in length. In general, miRNA functions as the post translational regulation in eukaryotic cells. Regarding its typical characteristics, especially in several cancers, with two prominent properties, namely the circu...

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Main Authors: Lao Đức Thuận, Nguyễn Bảo Quốc, Trần Kiến Đức, Lê Huyền Ái Thúy
Format: Article
Language:English
Published: HO CHI MINH CITY OPEN UNIVERSITY JOURNAL OF SCIENCE 2015-11-01
Series:Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ
Subjects:
Online Access:https://journalofscience.ou.edu.vn/index.php/tech-vi/article/view/871
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author Lao Đức Thuận
Nguyễn Bảo Quốc
Trần Kiến Đức
Lê Huyền Ái Thúy
author_facet Lao Đức Thuận
Nguyễn Bảo Quốc
Trần Kiến Đức
Lê Huyền Ái Thúy
author_sort Lao Đức Thuận
collection DOAJ
description MicroRNA (miRNA) is the class of short non-coding RNA, about 21 nucleotides in length. In general, miRNA functions as the post translational regulation in eukaryotic cells. Regarding its typical characteristics, especially in several cancers, with two prominent properties, namely the circulating and the stability of miRNA in bio-fluid, the miRNA is noticed as the potential biomarker in prognosis and early diagnosis of cancer.In the current review, we aim to introduce the molecular, the characteristics and molecular mechanism of miRNA bio-synthesis, and the activities of miRNA. Moreover, we tend to analyse and apply them as the potential biomarker for cancer. This will be the prerequisite to understanding and developing the miRNA study in Vietnamese patients.
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2734-9594
language English
last_indexed 2024-12-21T01:41:43Z
publishDate 2015-11-01
publisher HO CHI MINH CITY OPEN UNIVERSITY JOURNAL OF SCIENCE
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series Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ
spelling doaj.art-ec889245f0de47d99239aa088d7accfe2022-12-21T19:20:09ZengHO CHI MINH CITY OPEN UNIVERSITY JOURNAL OF SCIENCETạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ2734-93222734-95942015-11-011014452737MICRO-RNA – A Potential Biomarker In CancerLao Đức Thuận0Nguyễn Bảo Quốc1Trần Kiến Đức2Lê Huyền Ái Thúy3Trường Đại học Mở TP.HCMTrường Đại Học Nông LâmTrường Đại học Mở TP.HCMTrường Đại học Mở TP.HCMMicroRNA (miRNA) is the class of short non-coding RNA, about 21 nucleotides in length. In general, miRNA functions as the post translational regulation in eukaryotic cells. Regarding its typical characteristics, especially in several cancers, with two prominent properties, namely the circulating and the stability of miRNA in bio-fluid, the miRNA is noticed as the potential biomarker in prognosis and early diagnosis of cancer.In the current review, we aim to introduce the molecular, the characteristics and molecular mechanism of miRNA bio-synthesis, and the activities of miRNA. Moreover, we tend to analyse and apply them as the potential biomarker for cancer. This will be the prerequisite to understanding and developing the miRNA study in Vietnamese patients.https://journalofscience.ou.edu.vn/index.php/tech-vi/article/view/871micrornabềnlưu thôngdấu chứng sinh họcung thư
spellingShingle Lao Đức Thuận
Nguyễn Bảo Quốc
Trần Kiến Đức
Lê Huyền Ái Thúy
MICRO-RNA – A Potential Biomarker In Cancer
Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ
microrna
bền
lưu thông
dấu chứng sinh học
ung thư
title MICRO-RNA – A Potential Biomarker In Cancer
title_full MICRO-RNA – A Potential Biomarker In Cancer
title_fullStr MICRO-RNA – A Potential Biomarker In Cancer
title_full_unstemmed MICRO-RNA – A Potential Biomarker In Cancer
title_short MICRO-RNA – A Potential Biomarker In Cancer
title_sort micro rna a potential biomarker in cancer
topic microrna
bền
lưu thông
dấu chứng sinh học
ung thư
url https://journalofscience.ou.edu.vn/index.php/tech-vi/article/view/871
work_keys_str_mv AT laođucthuan micrornaapotentialbiomarkerincancer
AT nguyenbaoquoc micrornaapotentialbiomarkerincancer
AT trankienđuc micrornaapotentialbiomarkerincancer
AT lehuyenaithuy micrornaapotentialbiomarkerincancer