Pregnancy and portal hypertension a pathology view of physiologic changes
The coexistent of pregnancy and liver disease represent a complex clinical situation, besides the liver complications that present in pregnancy with a previous health liver, like intrahepatic cholestasis of pregnancy, acute fatty liver of pregnancy or HELLP syndrome with bleeding disorders and viral...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2006-07-01
|
| Series: | Annals of Hepatology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1665268119320162 |
| _version_ | 1831591146661347328 |
|---|---|
| author | Eric Lopez-Mendez Lourdes Avila-Escobedo |
| author_facet | Eric Lopez-Mendez Lourdes Avila-Escobedo |
| author_sort | Eric Lopez-Mendez |
| collection | DOAJ |
| description | The coexistent of pregnancy and liver disease represent a complex clinical situation, besides the liver complications that present in pregnancy with a previous health liver, like intrahepatic cholestasis of pregnancy, acute fatty liver of pregnancy or HELLP syndrome with bleeding disorders and viral hepatitis, the previous liver damage with portal hypertension associated represent a clear stated of hemodynamic changes which increased risk of variceal bleeding. The portal hypertension syndrome has a splanchnic blood flow increase. During pregnancy an hypervolemic stated developed as consequence there is an increased in portal flow that contributed to more portal pressure transmitted to the collaterals veins which increase variceal bleeding risk in this group of patients. The present review will focus on treatment options to prevent variceal bleeding in this clinical situation. |
| first_indexed | 2024-12-18T01:17:47Z |
| format | Article |
| id | doaj.art-ec8894e7f4b54d88a413f9904cc86743 |
| institution | Directory Open Access Journal |
| issn | 1665-2681 |
| language | English |
| last_indexed | 2024-12-18T01:17:47Z |
| publishDate | 2006-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Annals of Hepatology |
| spelling | doaj.art-ec8894e7f4b54d88a413f9904cc867432022-12-21T21:25:54ZengElsevierAnnals of Hepatology1665-26812006-07-0153219223Pregnancy and portal hypertension a pathology view of physiologic changesEric Lopez-Mendez0Lourdes Avila-Escobedo1Gastroenterology Department, National Institute of Medical Sciences and Nutrition Salvador Zubirán, Mexico City, Mexico; Address for correspondence:Gastroenterology Department, National Institute of Medical Sciences and Nutrition Salvador Zubirán, Mexico City, MexicoThe coexistent of pregnancy and liver disease represent a complex clinical situation, besides the liver complications that present in pregnancy with a previous health liver, like intrahepatic cholestasis of pregnancy, acute fatty liver of pregnancy or HELLP syndrome with bleeding disorders and viral hepatitis, the previous liver damage with portal hypertension associated represent a clear stated of hemodynamic changes which increased risk of variceal bleeding. The portal hypertension syndrome has a splanchnic blood flow increase. During pregnancy an hypervolemic stated developed as consequence there is an increased in portal flow that contributed to more portal pressure transmitted to the collaterals veins which increase variceal bleeding risk in this group of patients. The present review will focus on treatment options to prevent variceal bleeding in this clinical situation.http://www.sciencedirect.com/science/article/pii/S1665268119320162Portal hypertensionpregnancysplanchnic flow |
| spellingShingle | Eric Lopez-Mendez Lourdes Avila-Escobedo Pregnancy and portal hypertension a pathology view of physiologic changes Annals of Hepatology Portal hypertension pregnancy splanchnic flow |
| title | Pregnancy and portal hypertension a pathology view of physiologic changes |
| title_full | Pregnancy and portal hypertension a pathology view of physiologic changes |
| title_fullStr | Pregnancy and portal hypertension a pathology view of physiologic changes |
| title_full_unstemmed | Pregnancy and portal hypertension a pathology view of physiologic changes |
| title_short | Pregnancy and portal hypertension a pathology view of physiologic changes |
| title_sort | pregnancy and portal hypertension a pathology view of physiologic changes |
| topic | Portal hypertension pregnancy splanchnic flow |
| url | http://www.sciencedirect.com/science/article/pii/S1665268119320162 |
| work_keys_str_mv | AT ericlopezmendez pregnancyandportalhypertensionapathologyviewofphysiologicchanges AT lourdesavilaescobedo pregnancyandportalhypertensionapathologyviewofphysiologicchanges |