Early Growth and Neurologic Outcomes of Infants with Probable Congenital Zika Virus Syndrome

We report the early growth and neurologic findings of 48 infants in Brazil diagnosed with probable congenital Zika virus syndrome and followed to age 1–8 months. Most of these infants had microcephaly (86.7%) and craniofacial disproportion (95.8%). The clinical pattern included poor head growth with...

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Main Authors: Antonio Augusto Moura da Silva, Jucelia Sousa Santos Ganz, Patricia da Silva Sousa, Maria Juliana Rodvalho Doriqui, Marizelia Rodrigues Costa Ribeiro, Maria dos Remédios Freitas Carvalho Branco, Rejane Christine de Sousa Queiroz, Maria de Jesus Torres Pacheco, Flavia Regina Vieira da Costa, Francelena de Sousa Silva, Vanda Maria Ferreira Simões, Marcos Antonio Barbosa Pacheco, Fernando Lamy-Filho, Zeni Carvalho Lamy, Maria Teresa Seabra Soares de Britto e Alves
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2016-11-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/22/11/16-0956_article
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author Antonio Augusto Moura da Silva
Jucelia Sousa Santos Ganz
Patricia da Silva Sousa
Maria Juliana Rodvalho Doriqui
Marizelia Rodrigues Costa Ribeiro
Maria dos Remédios Freitas Carvalho Branco
Rejane Christine de Sousa Queiroz
Maria de Jesus Torres Pacheco
Flavia Regina Vieira da Costa
Francelena de Sousa Silva
Vanda Maria Ferreira Simões
Marcos Antonio Barbosa Pacheco
Fernando Lamy-Filho
Zeni Carvalho Lamy
Maria Teresa Seabra Soares de Britto e Alves
author_facet Antonio Augusto Moura da Silva
Jucelia Sousa Santos Ganz
Patricia da Silva Sousa
Maria Juliana Rodvalho Doriqui
Marizelia Rodrigues Costa Ribeiro
Maria dos Remédios Freitas Carvalho Branco
Rejane Christine de Sousa Queiroz
Maria de Jesus Torres Pacheco
Flavia Regina Vieira da Costa
Francelena de Sousa Silva
Vanda Maria Ferreira Simões
Marcos Antonio Barbosa Pacheco
Fernando Lamy-Filho
Zeni Carvalho Lamy
Maria Teresa Seabra Soares de Britto e Alves
author_sort Antonio Augusto Moura da Silva
collection DOAJ
description We report the early growth and neurologic findings of 48 infants in Brazil diagnosed with probable congenital Zika virus syndrome and followed to age 1–8 months. Most of these infants had microcephaly (86.7%) and craniofacial disproportion (95.8%). The clinical pattern included poor head growth with increasingly negative z-scores, pyramidal/extrapyramidal symptoms, and epilepsy.
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spelling doaj.art-ec8dabf5cbb94a2cafba3240a0c9443c2022-12-22T00:22:45ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592016-11-0122111953195610.3201/eid2211.160956Early Growth and Neurologic Outcomes of Infants with Probable Congenital Zika Virus SyndromeAntonio Augusto Moura da SilvaJucelia Sousa Santos GanzPatricia da Silva SousaMaria Juliana Rodvalho DoriquiMarizelia Rodrigues Costa RibeiroMaria dos Remédios Freitas Carvalho BrancoRejane Christine de Sousa QueirozMaria de Jesus Torres PachecoFlavia Regina Vieira da CostaFrancelena de Sousa SilvaVanda Maria Ferreira SimõesMarcos Antonio Barbosa PachecoFernando Lamy-FilhoZeni Carvalho LamyMaria Teresa Seabra Soares de Britto e AlvesWe report the early growth and neurologic findings of 48 infants in Brazil diagnosed with probable congenital Zika virus syndrome and followed to age 1–8 months. Most of these infants had microcephaly (86.7%) and craniofacial disproportion (95.8%). The clinical pattern included poor head growth with increasingly negative z-scores, pyramidal/extrapyramidal symptoms, and epilepsy.https://wwwnc.cdc.gov/eid/article/22/11/16-0956_articleZika virus infectiongrowthbirthweightepilepsymicrocephalycongenital abnormalities
spellingShingle Antonio Augusto Moura da Silva
Jucelia Sousa Santos Ganz
Patricia da Silva Sousa
Maria Juliana Rodvalho Doriqui
Marizelia Rodrigues Costa Ribeiro
Maria dos Remédios Freitas Carvalho Branco
Rejane Christine de Sousa Queiroz
Maria de Jesus Torres Pacheco
Flavia Regina Vieira da Costa
Francelena de Sousa Silva
Vanda Maria Ferreira Simões
Marcos Antonio Barbosa Pacheco
Fernando Lamy-Filho
Zeni Carvalho Lamy
Maria Teresa Seabra Soares de Britto e Alves
Early Growth and Neurologic Outcomes of Infants with Probable Congenital Zika Virus Syndrome
Emerging Infectious Diseases
Zika virus infection
growth
birthweight
epilepsy
microcephaly
congenital abnormalities
title Early Growth and Neurologic Outcomes of Infants with Probable Congenital Zika Virus Syndrome
title_full Early Growth and Neurologic Outcomes of Infants with Probable Congenital Zika Virus Syndrome
title_fullStr Early Growth and Neurologic Outcomes of Infants with Probable Congenital Zika Virus Syndrome
title_full_unstemmed Early Growth and Neurologic Outcomes of Infants with Probable Congenital Zika Virus Syndrome
title_short Early Growth and Neurologic Outcomes of Infants with Probable Congenital Zika Virus Syndrome
title_sort early growth and neurologic outcomes of infants with probable congenital zika virus syndrome
topic Zika virus infection
growth
birthweight
epilepsy
microcephaly
congenital abnormalities
url https://wwwnc.cdc.gov/eid/article/22/11/16-0956_article
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