Intramyocardial electrograms measurements in patients after heart transplantation
<p><strong>Background:</strong> Adequate detection and treatment of acute allograft rejection is one of the most important predictors of post-transplant survival of cardiac transplant recipients. Recently, a number of novel, non-invasive tools have allowed for earlier detection and...
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Format: | Article |
Language: | English |
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Slovenian Medical Association
2005-12-01
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Series: | Zdravniški Vestnik |
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Online Access: | http://vestnik.szd.si/index.php/ZdravVest/article/view/2181 |
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author | Bojan Vrtovec Tone Gabrijelčič Urška Breskvar Igor Zupan |
author_facet | Bojan Vrtovec Tone Gabrijelčič Urška Breskvar Igor Zupan |
author_sort | Bojan Vrtovec |
collection | DOAJ |
description | <p><strong>Background:</strong> Adequate detection and treatment of acute allograft rejection is one of the most important predictors of post-transplant survival of cardiac transplant recipients. Recently, a number of novel, non-invasive tools have allowed for earlier detection and better treatment of rejection episodes.</p><p><strong>Methods:</strong> Using the signal from a special pacemaker implanted during the transplant procedure, the intraventricular electrograms can be obtained. The amplitude and the conduction time of the intraventricular electrogram provide information on electrophysiological properties of ventricular myocardium. Due to edema and inflammation during acute rejection, the amplitude of the signal decreases and the conduction time is prolonged.</p><p><strong>Results:</strong> In Ljubljana Medical Center Transplantation Programme the measurement of intramyocardial electrograms has been shown to represent a reproducible and reliable methodology which led to fewer cardiac biopsy procedures and earlier and better treatment of cardiac allograft rejection.</p><p><strong>Conclusions:</strong> The analysis of intramyocardial electrograms is an important non-invasive tool which allows for better follow-up of cardiac transplant recipients and earlier detection and treatment of allograft rejection episodes.</p> |
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format | Article |
id | doaj.art-ec8e0ae0f4784fc8a7f9d96226c03876 |
institution | Directory Open Access Journal |
issn | 1318-0347 1581-0224 |
language | English |
last_indexed | 2024-12-20T20:19:41Z |
publishDate | 2005-12-01 |
publisher | Slovenian Medical Association |
record_format | Article |
series | Zdravniški Vestnik |
spelling | doaj.art-ec8e0ae0f4784fc8a7f9d96226c038762022-12-21T19:27:36ZengSlovenian Medical AssociationZdravniški Vestnik1318-03471581-02242005-12-017401667Intramyocardial electrograms measurements in patients after heart transplantationBojan VrtovecTone GabrijelčičUrška BreskvarIgor Zupan<p><strong>Background:</strong> Adequate detection and treatment of acute allograft rejection is one of the most important predictors of post-transplant survival of cardiac transplant recipients. Recently, a number of novel, non-invasive tools have allowed for earlier detection and better treatment of rejection episodes.</p><p><strong>Methods:</strong> Using the signal from a special pacemaker implanted during the transplant procedure, the intraventricular electrograms can be obtained. The amplitude and the conduction time of the intraventricular electrogram provide information on electrophysiological properties of ventricular myocardium. Due to edema and inflammation during acute rejection, the amplitude of the signal decreases and the conduction time is prolonged.</p><p><strong>Results:</strong> In Ljubljana Medical Center Transplantation Programme the measurement of intramyocardial electrograms has been shown to represent a reproducible and reliable methodology which led to fewer cardiac biopsy procedures and earlier and better treatment of cardiac allograft rejection.</p><p><strong>Conclusions:</strong> The analysis of intramyocardial electrograms is an important non-invasive tool which allows for better follow-up of cardiac transplant recipients and earlier detection and treatment of allograft rejection episodes.</p>http://vestnik.szd.si/index.php/ZdravVest/article/view/2181heart transplantationacute rejectionpacemakersevoked potentials |
spellingShingle | Bojan Vrtovec Tone Gabrijelčič Urška Breskvar Igor Zupan Intramyocardial electrograms measurements in patients after heart transplantation Zdravniški Vestnik heart transplantation acute rejection pacemakers evoked potentials |
title | Intramyocardial electrograms measurements in patients after heart transplantation |
title_full | Intramyocardial electrograms measurements in patients after heart transplantation |
title_fullStr | Intramyocardial electrograms measurements in patients after heart transplantation |
title_full_unstemmed | Intramyocardial electrograms measurements in patients after heart transplantation |
title_short | Intramyocardial electrograms measurements in patients after heart transplantation |
title_sort | intramyocardial electrograms measurements in patients after heart transplantation |
topic | heart transplantation acute rejection pacemakers evoked potentials |
url | http://vestnik.szd.si/index.php/ZdravVest/article/view/2181 |
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